{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:16:47Z","timestamp":1790338607820,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,8,27]],"date-time":"2013-08-27T00:00:00Z","timestamp":1377561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Brucellosis is one of the most common systemic zoonotic diseases transmitted by consumption of unpasteurized dairy products or by occupational contact with infected animals. Brucellosis is rare in renal transplant recipients. Only 3 cases have been reported in the literature. We report a case of brucellosis with hematologic and hepatobiliary complications in a patient 3\u00a0years after renal transplantation. The mean time from transplantation to the diagnosis of brucellosis in these 4 reported patients was 5.1\u00a0years (range 17\u00a0months to 13\u00a0years). All patients had fever and constitutional symptoms, and all attained clinical cure after combination antibiotic therapy. Given the small number of patients, further study is needed to identify the characteristics of brucellosis in renal transplant recipients. Drug interactions and acute renal failure developed in our patient during antibiotic treatment. Therefore, we should monitor the levels of immunosuppressive agents frequently. Several studies have shown <jats:italic>in vitro<\/jats:italic> susceptibilities of <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella melitensis<\/jats:italic> to tigecycline. In our patient, fever finally subsided after tigecycline administration. The minimum inhibitory concentration of tigecycline using <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>test was 0.094\u00a0\u03bcg\/mL. Tigecycline may be a potential option for treatment of brucellosis in the setting of transplantation.<\/jats:p>","DOI":"10.1111\/tid.12125","type":"journal-article","created":{"date-parts":[[2013,8,27]],"date-time":"2013-08-27T08:13:44Z","timestamp":1377591224000},"source":"Crossref","is-referenced-by-count":14,"title":["Brucellosis in a renal transplant recipient"],"prefix":"10.1111","volume":"15","author":[{"given":"I.\u2010W.","family":"Ting","sequence":"first","affiliation":[{"name":"Kidney Institute China Medical University Hospital Taichung Taiwan"},{"name":"School of Medicine China Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u2010W.","family":"Ho","sequence":"additional","affiliation":[{"name":"School of Medicine China Medical University Taichung Taiwan"},{"name":"Department of Internal Medicine China Medical University Hospital Taichung 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