{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T01:36:04Z","timestamp":1765157764088},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,9,9]],"date-time":"2013-09-09T00:00:00Z","timestamp":1378684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We investigated the effect of combined use of rituximab (<jats:styled-content style=\"fixed-case\">RTX<\/jats:styled-content>) and plasmapheresis (<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>) pre\u2010transplant on post\u2010transplant infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 196 patients undergoing living\u2010donor kidney transplantation at Seoul St. Mary's Hospital, all of whom underwent basiliximab induction therapy, were included in the study. They were divided into 3 groups: <jats:styled-content style=\"fixed-case\">RTX<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>\/intravenous immune globulin (<jats:styled-content style=\"fixed-case\">IVIG<\/jats:styled-content>) (the <jats:styled-content style=\"fixed-case\">RPI<\/jats:styled-content> group; <jats:italic>n<\/jats:italic>\u00a0=\u00a053), <jats:styled-content style=\"fixed-case\">RTX<\/jats:styled-content> monotherapy (the <jats:styled-content style=\"fixed-case\">RTX<\/jats:styled-content> group; <jats:italic>n<\/jats:italic>\u00a0=\u00a014), and control (the <jats:styled-content style=\"fixed-case\">CONT<\/jats:styled-content> group; <jats:italic>n<\/jats:italic>\u00a0=\u00a0129). We compared the post\u2010transplant infections in the 3 groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall prevalence of infection was significantly higher, and the infection\u2010free survival rate was lower, in the <jats:styled-content style=\"fixed-case\">RPI<\/jats:styled-content> group compared with the <jats:styled-content style=\"fixed-case\">RTX<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">CONT<\/jats:styled-content> groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). A trend toward more severe bacterial infections was seen in the <jats:styled-content style=\"fixed-case\">RPI<\/jats:styled-content> group compared with the other groups, and fungal infections developed only in the <jats:styled-content style=\"fixed-case\">RPI<\/jats:styled-content> group. After anti\u2010rejection therapy, a significantly higher rate of infection developed in the <jats:styled-content style=\"fixed-case\">RPI<\/jats:styled-content> group than in the other groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). In addition, the <jats:styled-content style=\"fixed-case\">RPI<\/jats:styled-content> group was an independent risk factor for the development of infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results show that in the setting of basiliximab induction, the use of combined <jats:styled-content style=\"fixed-case\">RTX<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content> therapy pre\u2010transplant significantly increases the risk for post\u2010transplant infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12135","type":"journal-article","created":{"date-parts":[[2013,9,9]],"date-time":"2013-09-09T06:08:52Z","timestamp":1378706932000},"page":"559-568","source":"Crossref","is-referenced-by-count":31,"title":["Combined use of rituximab and plasmapheresis pre\u2010transplant increases post\u2010transplant infections in renal transplant recipients with basiliximab induction therapy"],"prefix":"10.1111","volume":"15","author":[{"given":"B.H.","family":"Chung","sequence":"first","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.T.","family":"Yun","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.E.","family":"Ha","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.I.","family":"Kim","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Department of Surgery College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.S.","family":"Moon","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Department of Surgery College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.S.","family":"Choi","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.W.","family":"Park","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.W.","family":"Yang","sequence":"additional","affiliation":[{"name":"Transplant Research Center College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"},{"name":"Division of Nephrology Department of Internal Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.08140910"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.01178.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneph0967"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0b013e3282f02218"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2012.01462.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31819f12be"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2004.00214.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000080685.31697.FC"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707894"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03710411"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr215"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02017.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2011.552149"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.02085.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2012.01480.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181fa941b"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2007.00700.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-114-11-924"},{"key":"e_1_2_6_21_1","volume-title":"Handbook of Dialysis","author":"Daugirdas JT","year":"2006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-3274(03)00059-5"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000112934.12622.2B"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-08-3300"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa060068"},{"issue":"3","key":"e_1_2_6_26_1","first-page":"S1","article-title":"KDIGO clinical practice guideline for the care of kidney transplant recipients","volume":"9","year":"2009","journal-title":"Am J Transplant"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02785.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.10.1.86"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2003.tb00300.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1086\/318483"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12135","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12135","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T11:37:07Z","timestamp":1695987427000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,9]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1111\/tid.12135"],"URL":"https:\/\/doi.org\/10.1111\/tid.12135","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,9]]}}}