{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:29:48Z","timestamp":1790918988419,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T00:00:00Z","timestamp":1387411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n The epidemiology of nontuberculous mycobacteria (\n NTM<\/jats:styled-content>\n ) disease in solid organ transplant recipients is poorly defined.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We identified all solid organ transplant recipients with\n NTM<\/jats:styled-content>\n disease at a single center over a 7.5\u2010year period, and collected data on patient demographics, co\u2010morbidities, immunosuppressive medications, and rejection. We conducted a case\u2013control study to identify risk factors for disease, matching 3 control patients to each case patient by date of transplantation.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 34 cases of\n NTM<\/jats:styled-content>\n disease occurred during the study period, involving 6 single lung, 13 bilateral lung, 8 heart, 4 liver, 2 kidney, and 1 pancreas\u2010kidney recipients. Cases were predominantly male (24\/34), with a median age of 55\u00a0years (interquartile range [\n IQR<\/jats:styled-content>\n ]: 46\u201361\u00a0years), and developed after a median of 8\u00a0months post transplantation (\n IQR<\/jats:styled-content>\n : 2\u201387\u00a0months).\n \n M<\/jats:styled-content>\n ycobacterium abscessus\n <\/jats:italic>\n and\n \n M<\/jats:styled-content>\n ycobacterium avium\n <\/jats:italic>\n complex were the most common pathogens, and the lung (including pleura) was the most common site of disease. In the adjusted case\u2013control analysis, lung transplant recipients had the highest risk of\n NTM<\/jats:styled-content>\n disease.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Additional studies are needed to evaluate the role of targeted surveillance measures for\n NTM<\/jats:styled-content>\n disease in high\u2010risk patients, particularly lung transplant recipients, and to characterize the mechanisms of disease acquisition.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/tid.12170","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T03:34:42Z","timestamp":1387424082000},"page":"76-83","source":"Crossref","is-referenced-by-count":85,"title":["Risk factors for nontuberculous mycobacterial infections in solid organ transplant recipients: a case\u2013control study"],"prefix":"10.1111","volume":"16","author":[{"given":"S.A.","family":"Longworth","sequence":"first","affiliation":[{"name":"Department of Medicine Perelman School of Medicine of the University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Vinnard","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases & HIV Medicine Drexel University College of Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Lee","sequence":"additional","affiliation":[{"name":"Merck Sharp & Dohme, Corp. North Wales Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.D.","family":"Sims","sequence":"additional","affiliation":[{"name":"Bristol\u2010Myers Squibb Princeton New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.D.","family":"Barton","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases Perelman School of Medicine of the University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.A.","family":"Blumberg","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases Perelman School of Medicine of the University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200604-571ST"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2005.10.029"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02895.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2012.00753.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.8.4205-4207.2005"},{"issue":"3","key":"e_1_2_6_7_1","first-page":"286","article-title":"The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals","volume":"8","author":"Cegielski JP","year":"2004","journal-title":"Int J Tuberc Lung Dis"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115101"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/420746"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-009-0032-4"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/19.2.263"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1329-4"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1086\/323126"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000160417.39497.a9"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/25.5.948"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12170","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T19:55:37Z","timestamp":1696190137000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,19]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/tid.12170"],"URL":"https:\/\/doi.org\/10.1111\/tid.12170","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,19]]}}}