{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:51:28Z","timestamp":1788310288250,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:00:00Z","timestamp":1388707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parainfluenza infection is a cause of significant morbidity and mortality in allogeneic hematopoietic stem cell transplant (<jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>) patients. <jats:styled-content style=\"fixed-case\">DAS<\/jats:styled-content>181 is a novel antiviral agent with activity against influenza and parainfluenza. We report the first 2 cases, to our knowledge, of successful <jats:styled-content style=\"fixed-case\">DAS<\/jats:styled-content>181 use in ventilated <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> patients with severe parainfluenza lung disease.<\/jats:p>","DOI":"10.1111\/tid.12177","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T11:40:44Z","timestamp":1388749244000},"page":"141-144","source":"Crossref","is-referenced-by-count":40,"title":["<scp>DAS<\/scp>181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation"],"prefix":"10.1111","volume":"16","author":[{"given":"S.","family":"Chalkias","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts USA"},{"name":"Center for Virology and Vaccine Research Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.","family":"Mackenzie","sequence":"additional","affiliation":[{"name":"Center for Virology and Vaccine Research Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Gay","sequence":"additional","affiliation":[{"name":"Department of Medicine Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Dooley","sequence":"additional","affiliation":[{"name":"Research Pharmacy Pharmacy Department Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.M.","family":"Marty","sequence":"additional","affiliation":[{"name":"Department of Medicine Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.B.","family":"Moss","sequence":"additional","affiliation":[{"name":"Ansun BioPharma San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Li","sequence":"additional","affiliation":[{"name":"Ansun BioPharma San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.L.","family":"Routh","sequence":"additional","affiliation":[{"name":"Ansun BioPharma San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.R.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Center for Virology and Vaccine Research Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts USA"},{"name":"Department of Medicine Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.S.","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts USA"},{"name":"Center for Virology and Vaccine Research Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-08-371112"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis622"},{"key":"e_1_2_5_4_1","volume-title":"DAS181 in Patients with Parainfluenza","author":"National Institute of Allergy and Infectious Diseases","year":"2013"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir501"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2012.00718.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.3.573"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI25669"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2013.04.012"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/653621"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12045"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1086\/652498"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12177","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T23:56:19Z","timestamp":1696204579000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,3]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/tid.12177"],"URL":"https:\/\/doi.org\/10.1111\/tid.12177","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,3]]}}}