{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:30:41Z","timestamp":1791725441431,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T00:00:00Z","timestamp":1393891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Invasive fungal infections are a major cause of morbidity and mortality among solid organ transplant (<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>) and hematopoietic cell transplant (<jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content>) recipients, but few data have been reported on the epidemiology of endemic fungal infections in these populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen institutions belonging to the Transplant\u2010Associated Infection Surveillance Network prospectively enrolled <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content> recipients with histoplasmosis, blastomycosis, or coccidioidomycosis occurring between March 2001 and March 2006.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 70 patients (64 <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> recipients and 6 <jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content> recipients) had infection with an endemic mycosis, including 52 with histoplasmosis, 9 with blastomycosis, and 9 with coccidioidomycosis. The 12\u2010month cumulative incidence rate among <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> recipients for histoplasmosis was 0.102%. Occurrence of infection was bimodal; 28 (40%) infections occurred in the first 6\u00a0months post transplantation, and 24 (34%) occurred between 2 and 11\u00a0years post transplantation. Three patients were documented to have acquired infection from the donor organ. Seven <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> recipients with histoplasmosis and 3 with coccidioidomycosis died (16%); no <jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content> recipient died.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This 5\u2010year multicenter prospective surveillance study found that endemic mycoses occur uncommonly in <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HCT<\/jats:styled-content> recipients, and that the period at risk extends for years after transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12186","type":"journal-article","created":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T08:03:57Z","timestamp":1393920237000},"page":"213-224","source":"Crossref","is-referenced-by-count":170,"title":["Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant\u2010Associated Infection Surveillance Network (<scp>TRANSNET<\/scp>)"],"prefix":"10.1111","volume":"16","author":[{"given":"C.A.","family":"Kauffman","sequence":"first","affiliation":[{"name":"University of Michigan and Veterans Affairs Ann Arbor Healthcare System Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.G.","family":"Freifeld","sequence":"additional","affiliation":[{"name":"University of Nebraska Medical Center Omaha Nebraska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.R.","family":"Andes","sequence":"additional","affiliation":[{"name":"University of Wisconsin Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.W.","family":"Baddley","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham Medical Center and Veterans Affairs Medical Center Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Herwaldt","sequence":"additional","affiliation":[{"name":"University of Iowa Carver College of Medicine and University of Iowa Hospital and Clinics Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.C.","family":"Walker","sequence":"additional","affiliation":[{"name":"Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.D.","family":"Alexander","sequence":"additional","affiliation":[{"name":"Duke University Medical Center Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.J.","family":"Anaissie","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Benedict","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.I.","family":"Ito","sequence":"additional","affiliation":[{"name":"City of Hope Comprehensive Cancer Center Duarte California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.M.","family":"Knapp","sequence":"additional","affiliation":[{"name":"St. Jude Children's Research Hospital Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.M.","family":"Lyon","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.A.","family":"Marr","sequence":"additional","affiliation":[{"name":"Fred Hutchinson Cancer Research Center Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.A.","family":"Morrison","sequence":"additional","affiliation":[{"name":"University of Minnesota and 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