{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:42:50Z","timestamp":1762004570038},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T00:00:00Z","timestamp":1394668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Pneumocystis jirovecii<\/jats:italic> pneumonia (<jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content>) continues to be a leading cause of morbidity and mortality in kidney transplant recipients. Granulomatous <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> is an unusual histological presentation that has been described in a variety of immunosuppressive conditions. Previous studies have demonstrated an association between granulomatous disorders and hypercalcemia, the purported mechanism of which is extrarenal production of 1,25\u2010dihydroxyvitamin D by activated macrophages. Here, we report a case of granulomatous formation in a kidney transplant recipient with <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> who presented with hypercalcemia and suppressed parathyroid hormone, both of which resolved after successful treatment of the pneumonia. In immunocompromised patients, pulmonary infection associated with hypercalcemia should raise the suspicion of <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> and other granulomatous disorders.<\/jats:p>","DOI":"10.1111\/tid.12198","type":"journal-article","created":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T07:49:06Z","timestamp":1394696946000},"page":"315-319","source":"Crossref","is-referenced-by-count":18,"title":["<i><scp>P<\/scp>neumocystis jirovecii<\/i> pneumonia with an atypical granulomatous response after kidney transplantation"],"prefix":"10.1111","volume":"16","author":[{"given":"J.","family":"Ramalho","sequence":"first","affiliation":[{"name":"Nephrology Division Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.D.","family":"Bacelar Marques","sequence":"additional","affiliation":[{"name":"Renal Transplant Service Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.R.","family":"Aguirre","sequence":"additional","affiliation":[{"name":"Renal Transplant Service Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"Pierrotti","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.J.","family":"de Paula","sequence":"additional","affiliation":[{"name":"Renal Transplant Service Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.C.","family":"Nahas","sequence":"additional","affiliation":[{"name":"Renal Transplant Service Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"David\u2010Neto","sequence":"additional","affiliation":[{"name":"Renal Transplant Service Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,13]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00691.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.6.1111"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199007000-00002"},{"issue":"1","key":"e_1_2_4_5_1","first-page":"44","article-title":"Granulomatous response to Pneumocystis carinii in patients infected with HIV","volume":"10","author":"Kadakia J","year":"1993","journal-title":"Sarcoidosis"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/906832"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00623.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra032588"},{"issue":"3","key":"e_1_2_4_9_1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/ajcp\/63.3.384","article-title":"Pulmonary granulomatous pneumocystosis following renal transplantation. 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