{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:36:12Z","timestamp":1780443372415,"version":"3.54.1"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,4,12]],"date-time":"2014-04-12T00:00:00Z","timestamp":1397260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The optimal combination of galactomannan index (<jats:styled-content style=\"fixed-case\">GMI<\/jats:styled-content>) testing for the diagnosis of invasive pulmonary aspergillosis (<jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>) remains unclear. For diagnostic approaches that are triggered by clinical signs and symptoms in high\u2010risk patients, institutional variation remains, with some centers routinely relying on only serum <jats:styled-content style=\"fixed-case\">GMI<\/jats:styled-content> or bronchoalveolar lavage (<jats:styled-content style=\"fixed-case\">BAL<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">GMI<\/jats:styled-content> testing. In addition, use of mold\u2010active agents before diagnosis of <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content> is becoming increasingly common, and understanding the effect of these drugs on test yield is important when making time\u2010critical treatment decisions. In a single\u2010center cohort of 210 allogeneic hematopoietic cell transplant recipients, we found that serum and <jats:styled-content style=\"fixed-case\">BAL GMI<\/jats:styled-content> testing contributed independently to <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content> diagnosis, supporting the practice of sending both tests simultaneously to ensure a timely diagnosis of <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">BAL GMI<\/jats:styled-content> sensitivity was not affected by receipt of mold\u2010active therapy in our cohort.<\/jats:p>","DOI":"10.1111\/tid.12211","type":"journal-article","created":{"date-parts":[[2014,4,12]],"date-time":"2014-04-12T06:52:41Z","timestamp":1397285561000},"page":"505-510","source":"Crossref","is-referenced-by-count":18,"title":["Independent contribution of bronchoalveolar lavage and serum galactomannan in the diagnosis of invasive pulmonary aspergillosis"],"prefix":"10.1111","volume":"16","author":[{"given":"C.E.","family":"Fisher","sequence":"first","affiliation":[{"name":"Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle Washington USA"},{"name":"Division of Allergy and Infectious Diseases University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Stevens","sequence":"additional","affiliation":[{"name":"Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Leisenring","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Washington Seattle Washington USA"},{"name":"Clinical Statistics Fred Hutchinson Cancer Research Center Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.A.","family":"Pergam","sequence":"additional","affiliation":[{"name":"Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle Washington USA"},{"name":"Division of Allergy and Infectious Diseases University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Boeckh","sequence":"additional","affiliation":[{"name":"Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle Washington USA"},{"name":"Division of Allergy and Infectious Diseases University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.M.","family":"Hohl","sequence":"additional","affiliation":[{"name":"Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle Washington USA"},{"name":"Division of Allergy and Infectious Diseases University of Washington Seattle Washington USA"},{"name":"Infectious Disease Service Department of Medicine Memorial Sloan\u2010Kettering Cancer Center New York New York 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Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12211","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:25:04Z","timestamp":1695569104000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,12]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/tid.12211"],"URL":"https:\/\/doi.org\/10.1111\/tid.12211","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,12]]}}}