{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:05:29Z","timestamp":1718150729667},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T00:00:00Z","timestamp":1404691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Renal transplant recipients may present with intracranial space\u2010occupying lesions (<jats:styled-content style=\"fixed-case\">SOL<\/jats:styled-content>s) due to infections as well as a post\u2010transplant lymphoproliferative disorder (<jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content>). Here, we discuss a renal transplant recipient who presented with neurologic symptoms and magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) of the brain showed multiple focal <jats:styled-content style=\"fixed-case\">SOL<\/jats:styled-content>s. Tuberculosis (<jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content>), toxoplasmosis, nocardiosis, fungal infections, and <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content> were considered in the differential diagnosis. <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> spectroscopy was suggestive of an infectious cause, such as toxoplasmosis or <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content>. Serologic tests using <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>oxoplasma<\/jats:italic> were negative. A brain biopsy followed by immunohistochemical staining using <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>oxoplasma<\/jats:italic> antibody demonstrated multiple intravascular cysts of toxoplasma. This case highlights the diagnostic dilemma in an immunocompromised patient with multiple focal brain lesions, especially in areas where <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content> is endemic.<\/jats:p>","DOI":"10.1111\/tid.12262","type":"journal-article","created":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T06:03:00Z","timestamp":1404712980000},"page":"838-842","source":"Crossref","is-referenced-by-count":3,"title":["Multiple intracranial space\u2010occupying lesions in a renal transplant recipient from an area endemic for tuberculosis (<scp>TB<\/scp>): <scp>TB<\/scp> vs. toxoplasmosis"],"prefix":"10.1111","volume":"16","author":[{"given":"S.","family":"Bagchi","sequence":"first","affiliation":[{"name":"Department of Nephrology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.S.","family":"Sachdev","sequence":"additional","affiliation":[{"name":"Department of Nephrology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Nalwa","sequence":"additional","affiliation":[{"name":"Department of Pathology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.J.","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Radiology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Suri","sequence":"additional","affiliation":[{"name":"Department of Pathology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Department of Nephrology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Bhowmik","sequence":"additional","affiliation":[{"name":"Department of Nephrology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Nephrology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2000.020302.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61579-1"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1309\/N82CTQ1J0XEVEFQB"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir508"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir806"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1645\/GE-1159.1"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02915.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.7.3544-3547.2005"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2007.00244.x"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12262","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12262","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:23:47Z","timestamp":1695551027000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,7]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1111\/tid.12262"],"URL":"https:\/\/doi.org\/10.1111\/tid.12262","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,7]]}}}