{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:34:37Z","timestamp":1784194477212,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,7,12]],"date-time":"2014-07-12T00:00:00Z","timestamp":1405123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chagas disease is a lifelong, systemic, parasitic infection caused by the protozoan <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>rypanosoma cruzi<\/jats:italic>. The main form of disease transmission is vector borne, but vertical transmission, such as by organ transplantation from a chronically infected donor, is also possible. The brain tumor\u2010like form can occur years after infection and has been described in patients with acquired immunodeficiency syndrome, and in a very few cases in transplant recipients. We describe the case of a kidney transplant patient who was human immunodeficiency virus negative and infected with <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>.\u00a0cruzi<\/jats:italic>, and developed cerebral trypanosomiasis that was successfully treated with benznidazole at 7\u00a0mg\/kg\/day for 60\u00a0days. The risk of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hagas disease transmission should not be underestimated in renal transplant patients, even in non\u2010endemic areas. <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hagas disease can present as a tumor\u2010like brain lesion, very difficult to differentiate from other opportunistic infectious or neoplastic processes. Frequent monitoring for <jats:italic><jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>.\u00a0cruzi<\/jats:italic> infection is essential to promptly implement treatment, which, in our patient, proved to be effective and safe.<\/jats:p>","DOI":"10.1111\/tid.12265","type":"journal-article","created":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T15:08:29Z","timestamp":1405436909000},"page":"813-817","source":"Crossref","is-referenced-by-count":18,"title":["Cerebral trypanosomiasis in a renal transplant recipient"],"prefix":"10.1111","volume":"16","author":[{"given":"F.","family":"Cicora","sequence":"first","affiliation":[{"name":"Renal Transplantation Hospital de Alta Complejidad JD Per\u00f3n Formosa Argentina"},{"name":"Foundation for Research and Assistance in Renal Disease (FINAER) Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Escurra","sequence":"additional","affiliation":[{"name":"Renal Transplantation Hospital de Alta Complejidad JD Per\u00f3n Formosa Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Bibolini","sequence":"additional","affiliation":[{"name":"Renal Transplantation Hospital de Alta Complejidad JD Per\u00f3n Formosa Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Petroni","sequence":"additional","affiliation":[{"name":"Renal Transplantation Hospital de Alta Complejidad JD Per\u00f3n Formosa Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Renal Transplantation Hospital de Alta Complejidad JD Per\u00f3n Formosa Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Roberti","sequence":"additional","affiliation":[{"name":"Foundation for Research and Assistance in Renal Disease (FINAER) Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60061-X"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMct1014204"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir956"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12120"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/598634"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12340"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/598931"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001965"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e328354f179"},{"key":"e_1_2_5_11_1","first-page":"128","article-title":"Chagas' disease and kidney donation","volume":"33","author":"M\u00e1rquez E","year":"2013","journal-title":"Nefrologia"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000437673.86339.82"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02915.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-011-0225-8"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2002000500009"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2007.12.007"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(92)90275-G"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2009.04.012"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1973.22.473"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.07.043"},{"key":"e_1_2_5_21_1","unstructured":"AfeltraJ Arsel\u00e1nS Barc\u00e1nL et\u00a0al.Evaluaci\u00f3n infectol\u00f3gica para receptores de trasplante de \u00f3rganos s\u00f3lidos. 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