{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T01:56:15Z","timestamp":1769046975230,"version":"3.49.0"},"reference-count":61,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,8,14]],"date-time":"2014-08-14T00:00:00Z","timestamp":1407974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although bacteremias caused by the 6<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>pathogens (<jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>nterococcus faecium<\/jats:italic>,<jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>taphylococcus aureus<\/jats:italic>,<jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>lebsiella pneumoniae<\/jats:italic>,<jats:italic><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>cinetobacter baumannii<\/jats:italic>,<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudomonas aeruginosa<\/jats:italic>, and<jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>nterobacter<\/jats:italic>species) have recently been highlighted as a serious complication in solid organ transplant (<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>), more information is urgently needed. We sought to investigate the frequency and clinical outcomes of<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>bacteremia in<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>and determine the risk factors for mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of bacteremia after<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>was reviewed. Risk factors for mortality caused by<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>bacteremia were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010four episodes of bacteremia were caused by<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>strains. Of these strains, 41 were caused by resistant<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>(<jats:styled-content style=\"fixed-case\">rESKAPE<\/jats:styled-content>) organisms. The only factor for bacteremia\u2010related mortality independently associated with<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>was septic shock (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>]\u00a0=\u00a021.017, 95% confidence interval [CI]\u00a0=\u00a05.038\u201387.682,<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). The factors for bacteremia\u2010related mortality independently associated with<jats:styled-content style=\"fixed-case\">rESKAPE<\/jats:styled-content>bacteremia were septic shock (OR\u00a0=\u00a016.558, 95% CI\u00a0=\u00a06.620\u2013104.668,<jats:italic>P<\/jats:italic>\u00a0=\u00a00.003) and age \u226540\u00a0years (OR\u00a0=\u00a07.521, 95% CI\u00a0=\u00a01.196\u201347.292,<jats:italic>P<\/jats:italic>\u00a0=\u00a00.031).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To improve the outcomes of transplantation, more effective therapeutic treatments are of paramount importance when older SOT recipients with bacteremia due to<jats:styled-content style=\"fixed-case\">ESKAPE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">rESKAPE<\/jats:styled-content>organisms present with septic shock.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12278","type":"journal-article","created":{"date-parts":[[2014,8,14]],"date-time":"2014-08-14T13:24:41Z","timestamp":1408022681000},"page":"767-774","source":"Crossref","is-referenced-by-count":36,"title":["Frequency and clinical outcomes of<scp>ESKAPE<\/scp>bacteremia in solid organ transplantation and the risk factors for mortality"],"prefix":"10.1111","volume":"16","author":[{"given":"Q.F.","family":"Ye","sequence":"first","affiliation":[{"name":"Department of Transplant Surgery The Third Xiangya Hospital Central South University Changsha Hunan China"},{"name":"Department of Transplant Surgery Zhongnan Hospital Wuhan University Wuhan Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery The Third Xiangya Hospital Central South University Changsha Hunan 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