{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:37:44Z","timestamp":1784299064032,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,11,5]],"date-time":"2015-11-05T00:00:00Z","timestamp":1446681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32NR013454"],"award-info":[{"award-number":["T32NR013454"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Little is known about the epidemiology of carbapenem\u2010resistant<jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>lebsiella pneumoniae<\/jats:italic>(<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>) bacteriuria following kidney transplantation. We determined the incidence of post\u2010transplant<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria in adults who underwent kidney transplant from 2007 to 2010 at 2 New York City centers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a case\u2013control study to identify factors associated with<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria compared with carbapenem\u2010susceptible<jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>. pneumoniae<\/jats:italic>(<jats:styled-content style=\"fixed-case\">CSKP<\/jats:styled-content>) bacteriuria, assessed whether<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria was associated with mortality or graft failure, and compared outcomes of treated episodes of<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">CSKP<\/jats:styled-content>bacteriuria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 1852 transplants, 20 (1.1%) patients developed<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria. Factors associated with<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria included receipt of multiple organs (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>] 4.7, 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 1.1\u201320.4), deceased\u2010donor allograft (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>5.9, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>1.3\u201326.8), transplant admission length of stay (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>1.1 per day, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>1.0\u20131.1), pre\u2010transplant<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>infection or colonization (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>18.3, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>2.0\u2013170.5), diabetes mellitus (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>2.8, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>1.0\u20137.8), and receipt of antimicrobials other than trimethoprim\u2010sulfamethoxazole (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>4.3, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>1.6\u201311.2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared to<jats:styled-content style=\"fixed-case\">CSKP<\/jats:styled-content>bacteriuria,<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria was associated with increased mortality (30% vs. 10%,<jats:italic>P<\/jats:italic>= 0.03) but not graft failure. Treated episodes of<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria were less likely to achieve microbiologic clearance (83% vs. 97%;<jats:italic>P<\/jats:italic>= 0.05) and more likely to recur within 3 months (50% vs. 22%,<jats:italic>P<\/jats:italic>= 0.02) than<jats:styled-content style=\"fixed-case\">CSKP<\/jats:styled-content>episodes.<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>bacteriuria after kidney transplant is associated with mortality and antimicrobial failure after treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12450","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T11:11:45Z","timestamp":1444734705000},"page":"800-809","source":"Crossref","is-referenced-by-count":86,"title":["Epidemiology and outcomes of carbapenem\u2010resistant<i><scp>K<\/scp>lebsiella pneumoniae<\/i>bacteriuria in kidney transplant recipients"],"prefix":"10.1111","volume":"17","author":[{"given":"S.M.","family":"Pouch","sequence":"first","affiliation":[{"name":"Department of Medicine The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.J.","family":"Kubin","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Medical Center New York New York USA"},{"name":"NewYork\u2010Presbyterian Hospital New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Satlin","sequence":"additional","affiliation":[{"name":"NewYork\u2010Presbyterian Hospital New York New York USA"},{"name":"Department of Medicine Weill Cornell Medical College New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.S.","family":"Tsapepas","sequence":"additional","affiliation":[{"name":"NewYork\u2010Presbyterian Hospital New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.R.","family":"Lee","sequence":"additional","affiliation":[{"name":"NewYork\u2010Presbyterian Hospital New York New York USA"},{"name":"Department of Medicine Weill Cornell Medical College New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Dube","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Medical Center New York New York USA"},{"name":"NewYork\u2010Presbyterian Hospital New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Medical Center New York New York USA"},{"name":"NewYork\u2010Presbyterian Hospital New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,5]]},"reference":[{"issue":"9","key":"e_1_2_6_2_1","first-page":"165","article-title":"Vital signs: carbapenem\u2010resistant Enterobacteriaceae","volume":"62","author":"Centers for Disease Control and Prevention","year":"2013","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/421495"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.7.3018-3020.2005"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/512370"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki175"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/591861"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70054-4"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/592412"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01020-07"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm356"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2010.02.001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2011.05.022"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.12.002"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740330802410462"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc2872"},{"key":"e_1_2_6_17_1","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing; 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