{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:55:32Z","timestamp":1773860132426,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,11,13]],"date-time":"2015-11-13T00:00:00Z","timestamp":1447372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Post\u2010transplant lymphoproliferative disorder (<jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content>) is one of the life\u2010threatening complications after hematopoietic stem cell transplantation (<jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>) and solid organ transplantation (<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>), and it is associated almost exclusively with Epstein\u2013Barr virus (<jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>). We herein report 2 cases of <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>\u2010associated <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content> after allogeneic <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> localized in the adrenal gland. Both patients developed adrenal tumor within 3 months after <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> and were successfully treated with rituximab or tapering immunosuppressive agents. Both remained alive without recurrence. A literature review revealed 12 reported cases of <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content> involving the adrenal gland, but the adrenal gland was involved as one of the lesions of advanced\u2010stage <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>. To the best of our knowledge, this is the first report to show cases of isolated <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>\u2010associated adrenal <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content> should be recognized as one of the causes of isolated adrenal tumor after <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/tid.12461","type":"journal-article","created":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T21:24:46Z","timestamp":1443734686000},"page":"909-914","source":"Crossref","is-referenced-by-count":4,"title":["Post\u2010transplant lymphoproliferative disorder of the adrenal gland after allogeneic hematopoietic stem cell transplantation: report of two cases and literature review"],"prefix":"10.1111","volume":"17","author":[{"given":"H.","family":"Kasahara","sequence":"first","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Mori","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kato","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Koda","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kohashi","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kikuchi","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Yamane","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Mikami","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Pathology Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Kameyama","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Pathology Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Medicine Keio University Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,11,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199012203232510"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.56.082103.104727"},{"issue":"4","key":"e_1_2_6_4_1","first-page":"1027","article-title":"The systemic distribution of Epstein\u2010Barr virus genomes in fatal post\u2010transplantation lymphoproliferative disorders. 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