{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:07:03Z","timestamp":1790759223968,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,30]],"date-time":"2016-01-30T00:00:00Z","timestamp":1454112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Few studies have been conducted in South America regarding the detection and genotyping of human papillomavirus (<jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>) in viral warts of renal transplant recipients (<jats:styled-content style=\"fixed-case\">RTRs<\/jats:styled-content>). The characterization of the population most susceptible to the development of warts and the knowledge of the main <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> types in this environment prompted this study, which focuses on the detection and typing of <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">RTR<\/jats:styled-content>s in Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010eight patients with viral warts from the Hospital S\u00e3o Paulo\/Federal University of S\u00e3o Paulo were included in this study. <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> was detected by polymerase chain reaction (<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>) using combinations of the following primers: <jats:styled-content style=\"fixed-case\">PGMY<\/jats:styled-content> 09\/11, <jats:styled-content style=\"fixed-case\">RK<\/jats:styled-content> 91, <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> 65\/70, and <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> 66\/69. Restriction fragment length polymorphism and automated sequencing techniques were used for <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> typing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> was detected by <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> in 89.7% of viral wart samples. The most frequently detected <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> types included 57, 27, 1a, 2a, and 20. Other types of <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>\u2010epidermodysplasia verruciformis were also detected, including 14, 15, 19, 20, 21, 23, 36, and 38. Rare <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> types were also detected in our environment, including <jats:styled-content style=\"fixed-case\">RTR<\/jats:styled-content> X1, <jats:styled-content style=\"fixed-case\">RTR<\/jats:styled-content> X7, and 100. The time after transplant was correlated with an increased number of lesions and beta papillomavirus genus infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> types detected in the <jats:styled-content style=\"fixed-case\">RTR<\/jats:styled-content> population were similar to those described in immunocompetent populations. However, the diversity of the <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> types identified and the number of lesions were increased in the <jats:styled-content style=\"fixed-case\">RTR<\/jats:styled-content> population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12479","type":"journal-article","created":{"date-parts":[[2015,11,5]],"date-time":"2015-11-05T13:38:06Z","timestamp":1446730686000},"page":"37-43","source":"Crossref","is-referenced-by-count":18,"title":["Human papillomavirus detected in viral warts of renal transplant recipients"],"prefix":"10.1111","volume":"18","author":[{"given":"F.","family":"Martelli\u2010Marzag\u00e3o","sequence":"first","affiliation":[{"name":"Department of Dermatology Federal University of S\u00e3o Paulo UNIFESP S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.F.","family":"Santos Junior","sequence":"additional","affiliation":[{"name":"Department of Psychopharmacology\/Laboratory Medicine 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