{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T20:12:08Z","timestamp":1772741528451,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bloodstream infections (<jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content>) are frequent and potentially severe complications in allogeneic hematopoietic stem cell transplant (<jats:styled-content style=\"fixed-case\">AHSCT<\/jats:styled-content>) recipients. In patients on steroids, surveillance blood cultures (<jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s) are routinely performed to detect asymptomatic <jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content> but their usefulness remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a 1\u2010year, observational, prospective, single\u2010center study to assess the utility of daily <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s in <jats:styled-content style=\"fixed-case\">AHSCT<\/jats:styled-content> recipients on steroids and a case\u2013control study to identify risk factors associated with positive <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s. All blood cultures (<jats:styled-content style=\"fixed-case\">BC<\/jats:styled-content>s) obtained from adults hospitalized in the <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> unit were prospectively studied throughout 1 year. Characteristics, treatments, and outcome of patients were retrieved from medical charts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3594 <jats:styled-content style=\"fixed-case\">BC<\/jats:styled-content>s were obtained in 177 patients, including 1450 <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s in 82 <jats:styled-content style=\"fixed-case\">AHSCT<\/jats:styled-content> recipients on steroids. In 33 patients, 103 <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s (7%) were positive. Low\u2010virulence bacteria were identified in 74% of episodes. When analyzing first episode of positive <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s (28 patients), 6 (21%) true <jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content> were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with positive <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s were receiving antibiotic treatment less frequently at the time of <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s (<jats:italic>P<\/jats:italic> &lt; 0.001) and had more frequently <jats:styled-content style=\"fixed-case\">BC<\/jats:styled-content>s obtained through central venous access (<jats:italic>P<\/jats:italic> &lt; 0.04) when compared to patients with negative <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s. Daily <jats:styled-content style=\"fixed-case\">SBC<\/jats:styled-content>s in <jats:styled-content style=\"fixed-case\">AHSCT<\/jats:styled-content> recipients on steroids only rarely identify <jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content> and clear benefit for patients could not be demonstrated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12552","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T20:37:26Z","timestamp":1464122246000},"page":"504-511","source":"Crossref","is-referenced-by-count":6,"title":["Usefulness of daily surveillance blood cultures in allogeneic hematopoietic stem cell transplant recipients on steroids: a 1\u2010year prospective study"],"prefix":"10.1111","volume":"18","author":[{"given":"M.\u2010A.","family":"Colombier","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases H\u00f4pital Saint Louis APHP Paris 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