{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T22:50:06Z","timestamp":1756075806466},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T00:00:00Z","timestamp":1470787200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Spontaneous bacterial peritonitis (<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>) carries appreciable morbidity and mortality in the pre\u2010liver transplant (<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>) setting. However, the occurrence of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> and its consequences in the post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> setting have not been well characterized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> occurring in post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> patients between January 2007 and December 2012. Outcomes were compared to a cohort of post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> patients with allograft failure and ascites without <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common indication for liver transplantation in this cohort was hepatitis C. A total of 29 episodes of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> in 21 patients were identified. <jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>scherichia coli<\/jats:italic> (19%) and <jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>lebsiella pneumoniae<\/jats:italic> (10%) were the most frequent pathogens identified. Six patients died during their first episode of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>. Ten patients were eventually listed for liver re\u2010transplantation (re\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>) after their first episode of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>; 5 of these patients were transplanted and the other 5 died. Of the 5 who were transplanted, 2 died shortly after re\u2010transplant, and 3 are still alive. The cause of death in the majority of patients was infection (83.3%). The median time from onset of ascites to death was 214\u00a0days (range: 10\u20131085\u00a0days) and from the first episode of <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> to death was 50.5\u00a0days (range: 4\u2013549\u00a0days). In contrast, the median time from onset of ascites to death in patients with allograft failure and ascites without <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> was 331.5\u00a0days (45\u20132400\u00a0days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Allograft failure with ascites is a poor prognostic factor and these patients should be considered high risk for re\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> may accelerate the time to mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12565","type":"journal-article","created":{"date-parts":[[2016,6,4]],"date-time":"2016-06-04T15:30:03Z","timestamp":1465054203000},"page":"545-551","source":"Crossref","is-referenced-by-count":3,"title":["Outcomes of spontaneous bacterial peritonitis in liver transplant recipients with allograft 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