{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T02:13:20Z","timestamp":1779934400222,"version":"3.53.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T00:00:00Z","timestamp":1482883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005865","name":"Mochida Memorial Foundation for Medical and Pharmaceutical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The prophylactic use of antifungal drugs in allogeneic hematopoietic cell transplant recipients has revealed that the rate of non<jats:italic>\u2010albicans<\/jats:italic> candidemia has increased. We herein report the case of a patient with adult T\u2010cell leukemia who developed candidemia due to <jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>andida fermentati<\/jats:italic> during micafungin treatment after cord blood transplantation. The isolate was identified on day 47 by sequencing of the internal transcribed spacer region of the ribosomal <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> gene. The sequencing of the hot spot region of fks1p of isolate revealed naturally occurring amino acid substitutions, which conferred reduced echinocandin susceptibility. This case highlights that breakthrough candidemia due to <jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>.\u00a0fermentati<\/jats:italic> occurred in a patient receiving micafungin treatment.<\/jats:p>","DOI":"10.1111\/tid.12634","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T18:40:16Z","timestamp":1479321616000},"source":"Crossref","is-referenced-by-count":10,"title":["Breakthrough fungemia due to <i><scp>C<\/scp>andida fermentati<\/i> with fks1p mutation under micafungin treatment in a cord blood transplant recipient"],"prefix":"10.1111","volume":"19","author":[{"given":"Takaaki","family":"Konuma","sequence":"first","affiliation":[{"name":"Department of Hematology\/Oncology The Institute of Medical Science The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Takahashi","sequence":"additional","affiliation":[{"name":"TechnoSuruga Laboratory Co., Ltd.  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