{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:08:32Z","timestamp":1772752112016,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T00:00:00Z","timestamp":1488758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Non\u2010<jats:italic>Candida<\/jats:italic> opportunistic yeasts are emerging causes of bloodstream infection (<jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content>) in immunocompromised hosts. However, their clinical presentation, management, and outcomes in stem cell transplant (<jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content>) recipients are not well described. We report the first case to our knowledge of <jats:italic>Pseudozyma <\/jats:italic><jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content> in a <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> recipient. He had evidence of cutaneous involvement, which has not been previously described in the literature. He became infected while neutropenic and receiving empiric micafungin, which is notable because <jats:italic>Pseudozyma<\/jats:italic> is reported to be resistant to echinocandins. He was successfully treated with the sequential use of liposomal amphotericin B and voriconazole. A review of the literature revealed nine reported instances of <jats:italic>Pseudozyma<\/jats:italic> fungemia. We performed a retrospective review of 3557 <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> recipients at our institution from January 2000 to June 2015 and identified four additional cases of non\u2010<jats:italic>Candida<\/jats:italic> yeast <jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content>s. These include two with <jats:italic>Cryptococcus<\/jats:italic>, one with <jats:italic>Trichosporon<\/jats:italic>, and one with <jats:italic>Saccharomyces<\/jats:italic>. <jats:italic>Pseudozyma<\/jats:italic> and other non\u2010<jats:italic>Candida<\/jats:italic> yeasts are emerging pathogens that can cause severe and disseminated infections in <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> recipients and other immunocompromised hosts. Clinicians should have a high degree of suspicion for echinocandin\u2010resistant yeasts, if patients develop breakthrough yeast <jats:styled-content style=\"fixed-case\">BSI<\/jats:styled-content>s while receiving echinocandin therapy.<\/jats:p>","DOI":"10.1111\/tid.12664","type":"journal-article","created":{"date-parts":[[2017,1,18]],"date-time":"2017-01-18T19:52:52Z","timestamp":1484769172000},"source":"Crossref","is-referenced-by-count":32,"title":["<i>Pseudozyma<\/i> and other non\u2010<i>Candida<\/i> opportunistic yeast bloodstream infections in a large stem cell transplant center"],"prefix":"10.1111","volume":"19","author":[{"given":"Anupam","family":"Pande","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Washington University School of Medicine  St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lemuel R.","family":"Non","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Washington University School of Medicine  St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rizwan","family":"Romee","sequence":"additional","affiliation":[{"name":"Bone Marrow Transplantation and Leukemia Section Division of Oncology Washington University School of Medicine  St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A. 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