{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T11:45:56Z","timestamp":1793965556740,"version":"4.8.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T00:00:00Z","timestamp":1495584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite careful donor screening, unexpected donor\u2010derived infections continue to occur in organ transplant recipients (<jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>s). Lymphocytic choriomeningitis virus (<jats:styled-content style=\"fixed-case\">LCMV<\/jats:styled-content>) is one such transplant\u2010transmitted infection that in previous reports has resulted in a high mortality among the affected <jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>s. We report a <jats:styled-content style=\"fixed-case\">LCMV<\/jats:styled-content> case cluster that occurred 3\u00a0weeks post\u2010transplant in three <jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>s who received allografts from a common organ donor in March 2013. Following confirmation of <jats:styled-content style=\"fixed-case\">LCMV<\/jats:styled-content> infection at Centers for Disease Control and Prevention, immunosuppression was promptly reduced and ribavirin and\/or intravenous immunoglobulin therapy were initiated in <jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>s. The liver recipient died, but right kidney recipients survived without significant sequelae and left kidney recipient survived acute <jats:styled-content style=\"fixed-case\">LCMV<\/jats:styled-content> infection with residual mental status deficit. Our series highlights how early recognition led to prompt therapeutic intervention, which may have contributed to more favorable outcome in the kidney transplant recipients.<\/jats:p>","DOI":"10.1111\/tid.12707","type":"journal-article","created":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T23:13:16Z","timestamp":1492643596000},"source":"Crossref","is-referenced-by-count":31,"title":["High clinical suspicion of donor\u2010derived disease leads to timely recognition and early intervention to treat solid organ transplant\u2010transmitted lymphocytic choriomeningitis virus"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7885-635X","authenticated-orcid":false,"given":"Gagan","family":"Mathur","sequence":"first","affiliation":[{"name":"Department of Pathology University of Iowa Carver College of Medicine  Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunal","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\u2010Infectious Diseases University of Iowa Carver College of Medicine  Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley","family":"Ford","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Iowa Carver College of Medicine  Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilana J.","family":"Schafer","sequence":"additional","affiliation":[{"name":"Viral Special Pathogens Branch Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridhar V.","family":"Basavaraju","sequence":"additional","affiliation":[{"name":"Office of Blood, Organ, and Other Tissue Safety Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Knust","sequence":"additional","affiliation":[{"name":"Viral Special Pathogens Branch Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wun\u2010Ju","family":"Shieh","sequence":"additional","affiliation":[{"name":"Infectious Disease Pathology Branch Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Hill","sequence":"additional","affiliation":[{"name":"Organ Donation Department Iowa Donor Network  North Liberty IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garret D.","family":"Locke","sequence":"additional","affiliation":[{"name":"Compliance &amp; 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