{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T05:16:08Z","timestamp":1768626968729,"version":"3.49.0"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,8,7]],"date-time":"2017-08-07T00:00:00Z","timestamp":1502064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In endemic regions, coccidioidomycosis causes substantial morbidity and mortality for patients receiving solid organ transplants. We aimed to demonstrate the effect of antifungal coccidioidal prophylaxis in heart transplant (<jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>) recipients. We retrospectively reviewed the electronic health records of all patients who received <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>s between October 19, 2005, and December 13, 2014. We collected information regarding antifungal regimens and determined whether patients subsequently developed infections. Our 174\u2010person cohort all received antifungal prophylaxis for at least 6\u00a0months (mean follow\u2010up, 53.8\u00a0months). One proven and one probable coccidioidal infection (each, 0.6%) occurred during the study period. The incidence of coccidioidomycosis was 0.6% at 1\u00a0year and 2.3% at 5\u00a0years. No cases of proven coccidioidomycosis occurred within 2\u00a0years after transplantation. No patients developed disseminated disease, and no sentinel events were attributed to coccidioidomycosis. Both fluconazole and voriconazole were well tolerated. In the absence of intolerance or contraindication, we suggest continuing a universal antifungal prophylactic regimen with fluconazole for at least 6\u201012\u00a0months in <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content> recipients residing in a coccidioidomycosis\u2010endemic area.<\/jats:p>","DOI":"10.1111\/tid.12744","type":"journal-article","created":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T09:09:17Z","timestamp":1499764157000},"source":"Crossref","is-referenced-by-count":23,"title":["Single\u2010center experience of antifungal prophylaxis for coccidioidomycosis in heart transplant recipients within an endemic area"],"prefix":"10.1111","volume":"19","author":[{"given":"Graham M.","family":"Lohrmann","sequence":"first","affiliation":[{"name":"Mayo Clinic School of Graduate Medical Education Mayo Clinic College of Medicine and Science  Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darko","family":"Vucicevic","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Mayo Clinic Hospital  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romy","family":"Lawrence","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chris Hani Baragwanath Academic Hospital  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Eric","family":"Steidley","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Mayo Clinic Hospital  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Scott","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Mayo Clinic Hospital  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimon","family":"Kusne","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Mayo Clinic Hospital  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janis E.","family":"Blair","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Mayo Clinic Hospital  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20654"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1406.009"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/323463"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/24.2.216"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780500147840"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2003.00005.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000260143.54103.0d"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.01169.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03328.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24055"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12144"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1086\/376527"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21826"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03772.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000441088.01723.ee"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12129"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200209150-00017"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31822e6e9a"},{"key":"e_1_2_8_21_1","first-page":"525","article-title":"Coccidioidomycosis and heart transplantation","volume":"12","author":"Hall KA","year":"1993","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis195"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12362"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/595846"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2011.01.005"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2013.02.004"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12186"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1348475"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2009.01061.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000202421.94822.f7"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:34:28Z","timestamp":1695555268000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,7]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/tid.12744"],"URL":"https:\/\/doi.org\/10.1111\/tid.12744","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,7]]},"article-number":"e12744"}}