{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T18:25:15Z","timestamp":1781029515368,"version":"3.54.1"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,9,4]],"date-time":"2017-09-04T00:00:00Z","timestamp":1504483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2017,10]]},"abstract":"Abstract<\/jats:title>We present the case of a young man with acute lymphoblastic leukemia who developed cytomegalovirus (CMV<\/jats:styled-content>) appendicitis after receiving alemtuzumab for acute refractory graft\u2010versus\u2010host disease after allogeneic hematopoietic stem cell transplantation (HSCT<\/jats:styled-content>). CMV<\/jats:styled-content> appendicitis is a rare complication; and we are reporting the first case to our knowledge of CMV<\/jats:styled-content> appendicitis following HSCT<\/jats:styled-content>. Our case highlights the importance of recognition of CMV<\/jats:styled-content> viral reactivation following the use of alemtuzumab. Using a preemptive strategy of checking CMV PCR<\/jats:styled-content>, with initiation of early effective treatment on detection of CMV<\/jats:styled-content> replication, may be appropriate following use of alemtuzumab in hematologic malignancies in patients after HSCT<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/tid.12747","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T14:52:42Z","timestamp":1500043962000},"source":"Crossref","is-referenced-by-count":7,"title":["Cytomegalovirus appendicitis after hematopoietic stem cell transplantation"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3236-3864","authenticated-orcid":false,"given":"Atul","family":"Kothari","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari D.","family":"Caradine","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Rico Crescencio","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Appalanaidu","family":"Sasapu","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Department of Medicine University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muthu K.","family":"Veeraputhiran","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Department of Medicine University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh","family":"Jethava","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Department of Medicine University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary J.","family":"Burgess","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine University of Arkansas for Medical Sciences Little Rock AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,4]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"904","article-title":"Cytomegalovirus appendicitis in a patient with acquired immune deficiency syndrome","volume":"86","author":"Dieterich DT","year":"1991","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2015.03.004"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-14-313"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.2750"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.10.3257"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2217\/imt.14.7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000071362.99021.D9"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2016.09.016"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/504811"},{"key":"e_1_2_5_11_1","volume-title":"The AST Handbook of Transplant Infections","author":"Razonable RR","year":"2011"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12747","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:33:09Z","timestamp":1695555189000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,4]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/tid.12747"],"URL":"https:\/\/doi.org\/10.1111\/tid.12747","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,4]]},"article-number":"e12747"}}