{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:13:13Z","timestamp":1793059993626,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T00:00:00Z","timestamp":1510272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This is the case of a 56\u2010year\u2010old man who underwent heart transplantation. Within the first postoperative days, his respiratory and limb muscles weakened, which was attributed to critical illness polyneuromyopathy (\n                    <jats:styled-content style=\"fixed-case\">CIPM<\/jats:styled-content>\n                    ). At day 70 post transplantation, he had increased liver enzyme levels and acute hepatitis E virus (\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    ) infection was diagnosed.\n                    <jats:styled-content style=\"fixed-case\">HEV RNA<\/jats:styled-content>\n                    was found in the serum, stools, and cerebrospinal fluid. Results of further investigations suggested a possible\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    \u2010related polyradiculoneuropathy. At transplantation, the patient was negative for immunoglobulin (Ig)G, IgM, and\n                    <jats:styled-content style=\"fixed-case\">HEV RNA<\/jats:styled-content>\n                    . A trace\u2010back procedure identified the source of infection and concluded that\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    infection was contracted from blood transfusion 12\u00a0days prior to transplantation from an\n                    <jats:styled-content style=\"fixed-case\">HEV RNA<\/jats:styled-content>\n                    \u2010positive donor. Tests of the organ donor for\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    were negative. Phylogenetic analysis revealed sequence homology between the\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    \u20103 strain of the patient and the\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    \u20103 strain of the blood donor. Despite ribavirin treatment, the patient died on day 153 post transplantation from multiorgan failure. In conclusion, patients with hepatitis or neuropathic illness who have received blood products should be screened for\n                    <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/tid.12784","type":"journal-article","created":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T23:26:38Z","timestamp":1506727598000},"source":"Crossref","is-referenced-by-count":20,"title":["Transfusion\u2010acquired hepatitis E infection misdiagnosed as severe critical illness polyneuromyopathy in a heart transplant patient"],"prefix":"10.1111","volume":"19","author":[{"given":"Julie","family":"Belliere","sequence":"first","affiliation":[{"name":"Department of Nephrology and Organ Transplantation CHU Rangueil  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Abravanel","sequence":"additional","affiliation":[{"name":"INSERM U1043 IFR\u2013BMT CHU Purpan  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