{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:55:06Z","timestamp":1772160906317,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T00:00:00Z","timestamp":1514937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Abstract<\/jats:title>\n \n The shortage of livers has led most transplant centers to use extended criteria donors. Hepatitis C virus (\n HCV<\/jats:styled-content>\n )\n RNA<\/jats:styled-content>\n \u2010positive donor organs are typically not given to patients who have cleared\n HCV<\/jats:styled-content>\n . A 64\u2010year\u2010old male with chronic hepatitis C, genotype 1b was listed for\n LT<\/jats:styled-content>\n with hepatocellular carcinoma. While on the waiting list, the patient was treated with sofosbuvir, ledipasvir, and ribavirin and achieved an\n HCV RNA<\/jats:styled-content>\n <15\u00a0IU\/mL by week 10. At week 18 of a planned 24\u2010week treatment course, the patient underwent deceased\u2010donor\n LT<\/jats:styled-content>\n and received an organ from an anti\u2010\n HCV<\/jats:styled-content>\n \u2010positive donor. Treatment was stopped at\n LT<\/jats:styled-content>\n . At week 3 post\n LT<\/jats:styled-content>\n ,\n HCV RNA<\/jats:styled-content>\n was detectable and revealed a genotype 3\n HCV<\/jats:styled-content>\n infection, compatible with transplantation of an organ with established infection. With retreatment with sofosbuvir, daclatasvir, and ribavirin for 12\u00a0weeks, the patient achieved a sustained virologic response. This report highlights how antiviral therapies can be used to optimize the outcomes of\n HCV<\/jats:styled-content>\n \u2010infected transplant patients.\n <\/jats:p>","DOI":"10.1111\/tid.12809","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T09:56:36Z","timestamp":1510307796000},"source":"Crossref","is-referenced-by-count":10,"title":["Use of a hepatitis C virus (\n HCV<\/scp>\n )\n RNA<\/scp>\n \u2010positive donor in a treated\n HCV RNA<\/scp>\n \u2010negative liver transplant recipient"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6597-3151","authenticated-orcid":false,"given":"Isabel","family":"Campos\u2010Varela","sequence":"first","affiliation":[{"name":"Universidade de Santiago de Compostela (CLINURSID) and Department of Internal Medicine Hospital of Santiago de Compostela Santiago de Compostela Spain"},{"name":"Department of Medicine University of California\u2010San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana Z.","family":"Agudelo","sequence":"additional","affiliation":[{"name":"Department of Medicine University of California\u2010San Francisco San Francisco CA USA"},{"name":"Department of Surgery University of California\u2010San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Medicine University of California\u2010San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Surgery University of California\u2010San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norah A.","family":"Terrault","sequence":"additional","affiliation":[{"name":"Department of Medicine University of California\u2010San Francisco San Francisco CA USA"},{"name":"Department of Surgery University of California\u2010San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.07.047"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13197"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2014.2038"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20849"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13976"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu643"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.09.023"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.04.008"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.05.045"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23396"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1611829"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165339"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2014.02.019"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000413"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw387"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.07.020"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.05.021"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12809","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12809","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T08:57:56Z","timestamp":1695459476000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,3]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/tid.12809"],"URL":"https:\/\/doi.org\/10.1111\/tid.12809","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.732112141.793568736","asserted-by":"object"}]},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,3]]},"article-number":"e12809"}}