{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:16:29Z","timestamp":1790745389548,"version":"4.1.0"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T00:00:00Z","timestamp":1523318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 27\u2010year\u2010old man with severe aplastic anemia underwent bone marrow transplantation from his <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content> identical brother in July 2016. Conditioning included <jats:styled-content style=\"fixed-case\">ATGAM<\/jats:styled-content> 30\u00a0mg\/kg for 3\u00a0days and Cyclophosphamide 50\u00a0mg\/kg for 4\u00a0days. The patient received several platelet and red blood cell transfusions before and after the conditioning. The patient received broad spectrum antibiotics and caspofungin because persistant febrile neutropenia without bacteriological or mycological documentation. Hemophagocytic syndrome was diagnosed on day +12. Steroids at 1\u00a0mg\/kg were started on day +12. Fever resolved the same day but resumed 3\u00a0days later associated to intravascular hemolysis with no schizocytes on blood smears and negative <jats:styled-content style=\"fixed-case\">DAT<\/jats:styled-content>. Thick blood film smears performed on day +26 revealed <jats:italic>Plasmodium falciparum<\/jats:italic> parasites (parasitemia\u00a0=\u00a020%). Except the level of parasitemia, there were no signs of gravity. Quinine was started on day 26 at a loading dose of 15\u00a0mg\/kg followed by 8\u00a0mg\/kg three times a day for 20 doses. Fever vanished after 2\u00a0days. Parasitemia cleared in 3\u00a0days and remained negative thereafter. Investigations revealed that the patient was transfused by a red cell unit harvested in a voluntary donor native of a malaria endemic country. <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> for <jats:italic>P.\u00a0falciparum<\/jats:italic> performed in this donor in the frame of investigations was positive. The patient is alive with a normal blood count 1\u00a0year after <jats:styled-content style=\"fixed-case\">BMT<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/tid.12887","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T03:34:09Z","timestamp":1521862449000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["<i>Plasmodium falciparum<\/i> infection transmitted by transfusion: A cause of hemophagocytic syndrome after bone marrow tranplantation in a non\u2010endemic country"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8197-6504","authenticated-orcid":false,"given":"Saloua","family":"Ladeb","sequence":"first","affiliation":[{"name":"Centre National de Greffe de Moelle Osseuse de Tunis  Tunis Tunisia"},{"name":"Facult\u00e9 de M\u00e9decine de Tunis Universit\u00e9 de Tunis El Manar  Tunis 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