{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:20:06Z","timestamp":1787016006826,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T00:00:00Z","timestamp":1525651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2018,8]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Revaccination after hematopoietic stem cell transplantation (\n HSCT<\/jats:styled-content>\n ) is necessary to compensate for the loss of immunological memory. The aims of this study were to evaluate the adherence to revaccination schedule and the humoral immune response to different vaccine antigens in\n HSCT<\/jats:styled-content>\n pediatric and young adult patients.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Patients submitted to\n HSCT<\/jats:styled-content>\n for over 3\u00a0years were recruited. After written informed consent, a questionnaire was filled in, the vaccination card was analyzed, a blood sample was collected and tested by\n ELISA<\/jats:styled-content>\n for diphtheria,\n Haemophilus influenzae<\/jats:italic>\n type b (Hib), hepatitis A, hepatitis B, tetanus, measles, rubella, and varicella antibodies.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Sixty\u2010three patients (mean age at\n HSCT<\/jats:styled-content>\n , 10.7\u00a0years) were evaluated. Forty\u2010one (65%) were male; 34 (54%) had allogeneic and 29 (46%), autologous\n HSCT<\/jats:styled-content>\n . Complete adherence to diphtheria revaccination was found in 79.4% patients and seropositivity was found in 92% of those who completed the revaccination schedule; for Hib, 68.3% adherence and 95.3% seropositivity were observed; for hepatitis A, 63.5% adherence and 92.5% seropositivity; for 3 doses of hepatitis B, 86.8% adherence and 79.2% seropositivity; for tetanus, 79.4% adherence and 100% seropositivity; for measles and rubella, 17.5% adherence and 100% seropositivity; for varicella, 7.9% adherence and 100% seropositivity. The existence of a Vaccination Center for Special Immunobiologicals in patients' municipality was positively associated with completed vaccine schedule; on the other hand, chronic\n GVHD<\/jats:styled-content>\n was negatively associated with revaccination adherence.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Hematopoietic stem cell transplantation patients showed good seropositivity rates after complete vaccination schedule. However, a low coverage rate was observed for live attenuated antigens.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/tid.12903","type":"journal-article","created":{"date-parts":[[2018,4,18]],"date-time":"2018-04-18T12:08:49Z","timestamp":1524053329000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Adherence and immune response to revaccination following hematopoietic stem cell transplantation at a pediatric onco\u2010hematology reference center"],"prefix":"10.1111","volume":"20","author":[{"given":"Fernanda","family":"Gouveia\u2010Alves","sequence":"first","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roseane","family":"Gouveia","sequence":"additional","affiliation":[{"name":"Hospital Samaritano S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria C.","family":"Ginani","sequence":"additional","affiliation":[{"name":"Hospital Samaritano S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Seber","sequence":"additional","affiliation":[{"name":"Hospital Samaritano S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle A.","family":"Kuramoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel F.A.","family":"Murad","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda G.","family":"Spina","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio S.","family":"Petrilli","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor G.","family":"Zecchin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celso","family":"Granato","sequence":"additional","affiliation":[{"name":"Department of Medicine Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Fleury Group S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabianne","family":"Carlesse","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7345-5477","authenticated-orcid":false,"given":"Maria Isabel","family":"de Moraes\u2010Pinto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2009.263"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2009.254"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12312"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.49"},{"key":"e_1_2_8_6_1","volume-title":"Manual dos centros de refer\u00eancia para imunobiol\u00f3gicos especiais","author":"Brasil. Minist\u00e9rio da Sa\u00fade. Funda\u00e7\u00e3o Nacional de Sa\u00fade (FUNASA)","year":"2001"},{"key":"e_1_2_8_7_1","volume-title":"Manual dos centros de refer\u00eancia para imunobiol\u00f3gicos especiais","author":"Brasil. Minist\u00e9rio da Sa\u00fade. Secretaria de Vigil\u00e2ncia em Sa\u00fade. Departamento de Vigil\u00e2ncia Das Doen\u00e7as Transmiss\u00edveis","year":"2014"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit816"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.patbio.2013.07.004"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1997.tb05093.x"},{"key":"e_1_2_8_11_1","first-page":"1","volume-title":"Module 3: tetanus","author":"Borrow R","year":"2006"},{"key":"e_1_2_8_12_1","first-page":"1","volume-title":"Module 2: diphtheria","author":"Scheifele DW","year":"2009"},{"key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1128\/cdli.3.1.84-88.1996","article-title":"Interlaboratory study evaluating quantitation of antibody to Haemophilus influenzae type b polysaccharide by enzyme\u2010linked immunosorbent assay","volume":"3","author":"Madore DV","year":"1996","journal-title":"Clin Diagn Lab Immunol"},{"key":"e_1_2_8_14_1","first-page":"1","volume-title":"Module 9: haemophilus influenzae type b","author":"Goldblatt D","year":"2007"},{"key":"e_1_2_8_15_1","first-page":"1","volume-title":"Module 18: hepatitis A","author":"Shouval D","year":"2011"},{"key":"e_1_2_8_16_1","first-page":"1","volume-title":"Module 22: hepatitis B","author":"Herck XV","year":"2012"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/173.5.1077"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.5.1036"},{"key":"e_1_2_8_19_1","first-page":"1","volume-title":"Module 11: rubella","author":"Best JM","year":"2008"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652004000300008"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2006.01.017"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24186"},{"key":"e_1_2_8_23_1","first-page":"1","volume-title":"Module 7: measles","author":"Moss WJ","year":"2009"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/511641"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08913.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700909"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2010.31"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2014.290"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/153.5.840"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12110"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2015.10.006"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2009.01698.x"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12361"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/v6041590"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2011.09.014"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.12903","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.12903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T11:54:05Z","timestamp":1694951645000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.12903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,7]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1111\/tid.12903"],"URL":"https:\/\/doi.org\/10.1111\/tid.12903","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,7]]},"assertion":[{"value":"2017-09-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12903"}}