{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T13:07:34Z","timestamp":1774098454690,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T00:00:00Z","timestamp":1528848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The incidence of urinary tract infection (<jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>) after kidney transplantation (<jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>) caused by multidrug\u2010resistant (<jats:styled-content style=\"fixed-case\">MDR<\/jats:styled-content>) bacteria is growing. The aim of this study was to analyze the impact of <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> caused by carbapenem\u2010resistant Gram\u2010negative bacteria (<jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GNB<\/jats:styled-content>) in the survival of graft and recipients following <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>. This was a retrospective cohort study involving patients who underwent <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> between 2013 and 2016. Patients were followed since the day of the <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> until loss of graft, death or end of the follow\u2010up period (31th December 2016). The outcomes measured were <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> by <jats:styled-content style=\"fixed-case\">MDR<\/jats:styled-content> following <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> and graft and patient survival. Analyses were performed using Cox regression; for the graft and patient survival analysis, we used a propensity score for <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> by <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GNB<\/jats:styled-content> to matching a control group. <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> was diagnosed in 178 (23.9%) of 781 patients, who developed 352 <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> episodes. 44.6% of the <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> cases were caused by <jats:styled-content style=\"fixed-case\">MDR<\/jats:styled-content> bacteria. Identified risk factors for <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> by <jats:styled-content style=\"fixed-case\">MDR<\/jats:styled-content> bacteria were <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>, urologic disease as the cause of end\u2010stage renal failure, insertion of ureteral stent, carbapenem use, and delayed graft function (<jats:styled-content style=\"fixed-case\">DGF<\/jats:styled-content>). Risk factors for death during the follow\u2010up period were female gender, patients over 60\u00a0years old at the time of <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> DM<\/jats:styled-content>, body mass index over 31.8, <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> caused by <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GNB<\/jats:styled-content>. In conclusion, <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>s caused by <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GNB<\/jats:styled-content> have great impact on patients\u2019 survival after <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/tid.12923","type":"journal-article","created":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T17:55:17Z","timestamp":1527184517000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Does the urinary tract infection caused by carbapenem\u2010resistant Gram\u2010negative bacilli impact the outcome of kidney transplant recipients?"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9691-192X","authenticated-orcid":false,"given":"Maristela Pinheiro","family":"Freire","sequence":"first","affiliation":[{"name":"Working Committee for Hospital Epidemiology and Infection Control Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara V.","family":"Mendes","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Affonso C.","family":"Piovesan","sequence":"additional","affiliation":[{"name":"Renal Transplantation Unit Department of Urology Hospital das Cl\u00ednicas University of S\u00e3o Paulo School of Medicine  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavio Jota","family":"de Paula","sequence":"additional","affiliation":[{"name":"Renal Transplantation Unit Department of Urology 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