{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T09:51:18Z","timestamp":1781344278608,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T00:00:00Z","timestamp":1529625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2018,10]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>Berlin Heart\u00ae<\/jats:sup> EXCOR<\/jats:styled-content> devices (BHED<\/jats:styled-content>) are ventricular assist devices (VAD<\/jats:styled-content>) used mainly as a bridge to heart transplantation (HT<\/jats:styled-content>) in pediatric population. The aim of our study is to report the infections diagnosed in adult patients undergoing a BHED<\/jats:styled-content> implantation.<\/jats:p><\/jats:sec>Methods<\/jats:title>Adult patients receiving a BHED<\/jats:styled-content> between Jul 2009 and Oct 2017 at our institution were included. Infections were classified according to the International Society of Heart and Lung Transplantation definitions in VAD<\/jats:styled-content>\u2010Specific (VAD<\/jats:styled-content>\u2010S), VAD<\/jats:styled-content>\u2010Related (VAD<\/jats:styled-content>\u2010R) and non\u2010VAD<\/jats:styled-content> (N\u2010VAD<\/jats:styled-content>).<\/jats:p><\/jats:sec>Results<\/jats:title>Fifteen patients underwent BHED<\/jats:styled-content> implantation, which was maintained for a mean of 92 (19\u2010195) days. Infection occurred in 13 patients who developed 36 infectious episodes: 5 VAD<\/jats:styled-content>\u2010S (5 cannula infections); 8 VAD<\/jats:styled-content>\u2010R (5 bloodstream infections and 3 mediastinitis) and 24\u00a0N\u2010VAD<\/jats:styled-content> (7 urinary tract infections, 6 Cytomegalovirus diseases and others). Overall, 27 (75%) were bacterial, 7 (19.4%) were viral and there was one (2.7%) fungal infection. Eleven patients underwent HT<\/jats:styled-content> and all of them developed at least one infection after it. In 3 cases, all VAD<\/jats:styled-content>\u2010R or VAD<\/jats:styled-content>\u2010S infections were caused by the same etiology as before HT<\/jats:styled-content>. Their median time of appearance was on day +6 (3\u201011) after BHED<\/jats:styled-content> removal and HT<\/jats:styled-content>. Overall mortality was 6\/15 (40%). None of the deaths were related to VAD<\/jats:styled-content> Infection.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Infection complicated BHED<\/jats:styled-content> implantation in 86.7% of the patients. Overall, 13.9% were specific of BHED<\/jats:styled-content> and 22.2% were related. However, infections did not preclude HT<\/jats:styled-content> in any case and carried no attributable mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12936","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T13:35:50Z","timestamp":1527687350000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Infections in patients after Berlin Heart\u00ae<\/sup>EXCOR<\/scp> assist device implantation"],"prefix":"10.1111","volume":"20","author":[{"given":"Patricia","family":"Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Diseases Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica Gregorio Mara\u00f1\u00f3n Madrid Spain"},{"name":"Department of Medicine Universidad Complutense de Madrid Madrid Spain"},{"name":"CIBERES Madrid 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Cardiology Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iago","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Zatarain","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Barrio","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Hospital General 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