{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:05:19Z","timestamp":1787162719376,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T00:00:00Z","timestamp":1532044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Letermovir was approved by the Food and Drug Administration (\n                    <jats:styled-content style=\"fixed-case\">FDA<\/jats:styled-content>\n                    ) in November 2017 for use in adult cytomegalovirus (\n                    <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                    )\u2010seropositive allogeneic stem cell transplant (\n                    <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content>\n                    ) recipients for primary prophylaxis of\n                    <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                    infection and disease. We report off\u2010label use of letermovir for secondary prophylaxis of genotype\u2010confirmed ganciclovir\u2010resistant cytomegalovirus (\n                    <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\n                    ) syndrome (\n                    <jats:styled-content style=\"fixed-case\">UL<\/jats:styled-content>\n                    97 mutation [C603W]) in a heart transplant recipient initially treated with intravenous cidofovir followed by foscarnet, both discontinued due to unacceptable toxicities.\n                  <\/jats:p>","DOI":"10.1111\/tid.12965","type":"journal-article","created":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T06:55:52Z","timestamp":1531205752000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Letermovir successfully used for secondary prophylaxis in a heart transplant recipient with ganciclovir\u2010resistant cytomegalovirus syndrome (\n                    <scp>UL<\/scp>\n                    97 mutation)"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2475-7932","authenticated-orcid":false,"given":"Pearlie P.","family":"Chong","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagny","family":"Teiber","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie C.","family":"Prokesch","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reuben J.","family":"Arasaratnam","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Peltz","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark H.","family":"Drazner","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Garg","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00009-10"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/382753"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/135965350901400512"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/338143"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(02)00463-1"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/342385"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12103"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002191"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001418"},{"key":"e_1_2_5_11_1","first-page":"269","article-title":"Letermovir and inhibitors of the terminase complex: a 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