{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:37:09Z","timestamp":1776692229101,"version":"3.51.2"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T00:00:00Z","timestamp":1543968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Urinary tract infections are frequent complications early after kidney transplantation, and the use of antimicrobial coated catheters in settings other than transplantation has shown promising results for infection prevention. The purpose of this study was to compare the efficacy of Nitrofurazone\u2010coated silicone urinary catheters with non\u2010impregnated silicone urinary catheters in reducing bacteriuria and urinary tract infections in kidney transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This single\u2010center study, randomized controlled trial at the Hospital do Rim, a tertiary referral center in kidney transplantation, located in S\u00e3o Paulo, Brazil. Subjects involved living donor kidney transplant recipients, and were randomized 1:1 ratio with a computer\u2010generated system to a Nitrofurazone\u2010coated silicone urinary catheter and non\u2010impregnated silicone urinary catheter from March 2013 to December 2014. Patients with asymptomatic bacteriuria or urinary tract infection at baseline, deceased kidney transplant donors, patients with known hypersensitivity to nitrofurantoin, pregnancy, and those refusing to sign the informed consent form were excluded from the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred fourteen subjects were randomized and one hundred seventy\u2010six completed the study. There were no differences in the rates of asymptomatic bacteriuria (12.5% in the Nitrofurazone group and 11.4% in the control group, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.99) and urinary tract infection (8% and 6.8%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.99) and the incidence of side effects was more frequent in the Nitrofurazone\u2010impregnated silicone urinary catheter group (46.6% and 26.1%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study suggests that there is no beneficial effect of the employment of Nitrofurazone\u2010coated urinary catheter. Trial registration number: ISRCTN57888785.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13031","type":"journal-article","created":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T14:46:36Z","timestamp":1542638796000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["A randomized clinical trial comparing Nitrofurazone\u2010coated and uncoated urinary catheters in kidney transplant recipients: Results from a pilot study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0362-5992","authenticated-orcid":false,"given":"Fernando Gatti","family":"Menezes","sequence":"first","affiliation":[{"name":"Infection Control and Prevention Service Hospital Israelita Albert Einstein S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luci","family":"Corr\u00eaa","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Internal Medicine Department Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Osmar","family":"Medina\u2010Pestana","sequence":"additional","affiliation":[{"name":"Nephrology Division Hospital do Rim, Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson Ferreira","family":"Aguiar","sequence":"additional","affiliation":[{"name":"Urology Division Hospital do Rim, Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Fernando Aranha","family":"Camargo","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Internal Medicine Department Universidade Federal de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12366"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12465"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000120"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13075"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182a04997"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/675718"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2004.02.013"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/mic.2002.120128"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)80313-1"},{"key":"e_1_2_7_11_1","first-page":"152","article-title":"Assessment of nosocomial urinary tract infections in orthopaedic patients: a prospective and comparative study using two different catheters","volume":"88","author":"Al\u2010Habdan I","year":"2003","journal-title":"Int Surg"},{"key":"e_1_2_7_12_1","first-page":"1","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing; 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