{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:30:32Z","timestamp":1767652232608,"version":"3.41.2"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T00:00:00Z","timestamp":1553817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Crusted scabies is a rare disease variant associated with T\u2010cell dysregulation. Transplant patients are at risk of developing crusted scabies as a consequence of their immunosuppressive regimens. We report a case of crusted scabies presenting with recurrent septicemia in a 65\u2010year\u2010old renal transplant recipient, treated with daily ivermectin for 7\u00a0days after initial failure of weekly ivermectin dosing. A literature review of crusted scabies in transplant recipients consisting of 19 cases reports was summarized. Pruritus was common, and initial misdiagnosis was frequent. Most were treated with topical therapy, with one\u2010third receiving ivermectin. Three of seven cases presenting with a concomitant infection died. Crusted scabies is commonly misdiagnosed in transplant recipients owing to its rarity, varied appearance, and different skin distributions. It should be considered in the differential diagnosis of transplant recipients presenting with rash and pruritus, given its association with secondary infection and subsequent mortality.<\/jats:p>","DOI":"10.1111\/tid.13077","type":"journal-article","created":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T08:48:26Z","timestamp":1552639706000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Crusted scabies in a renal transplant recipient treated with daily ivermectin: A case report and literature review"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4949-3235","authenticated-orcid":false,"given":"Michael Ke","family":"Wang","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Chin\u2010Yee","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carson Ka\u2010Lok","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Medicine Queen's University Kingston Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"El\u2010Helou","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salem","family":"Alowami","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azim","family":"Gangji","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Ribic","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,29]]},"reference":[{"issue":"22","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1001\/jama.1981.03320220058027","article-title":"Norwegian scabies in a renal transplant patient","volume":"246","author":"Youshock E","year":"1981","journal-title":"JAMA"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.53128"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)63983-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2004.08.033"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31819b9a71"},{"issue":"1","key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1001\/archderm.1976.01630250037011","article-title":"Scabies simulating Darier disease in an immunosuppressed host","volume":"112","author":"Anolik MA","year":"1976","journal-title":"Arch Dermatol"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2008.00478.x"},{"issue":"2","key":"e_1_2_8_9_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1001\/archderm.1976.01630260017005","article-title":"Norwegian scabies: occurrence in a patient undergoing immunosuppression","volume":"112","author":"Espy PD","year":"1976","journal-title":"Arch Dermatol"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-011-1758-x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2011.05.014"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000188866"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5886.211"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.65302"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb07826.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.1985.11699070"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sft009"},{"issue":"1","key":"e_1_2_8_18_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1001\/archderm.1987.01660250101029","article-title":"Crusted (Norwegian) scabies. Occurrence in a child undergoing a bone marrow transplant","volume":"123","author":"Barnes L","year":"1987","journal-title":"Arch Dermatol"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0399-077X(04)00152-0"},{"issue":"5","key":"e_1_2_8_20_1","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1684\/ejd.2016.2827","article-title":"Crusted scabies in a liver transplant patient mimicking rupioid psoriasis","volume":"26","author":"Garofalo V","year":"2016","journal-title":"Eur J Dermatol"},{"issue":"5","key":"e_1_2_8_21_1","first-page":"584","article-title":"Crusted scabies and multiple dosages of ivermectin","volume":"12","author":"Ortega\u2010Loayza AG","year":"2013","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2018.07199"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1086\/313466"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra033540"},{"issue":"2","key":"e_1_2_8_25_1","first-page":"565","article-title":"Histocompatibility (HLA) antigens in Egyptians with two parasitic skin diseases (scabies and leishmaniasis)","volume":"20","author":"Morsy TA","year":"1990","journal-title":"J Egypt Soc Parasitol"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1981.tb00955.x"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04555.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2003.014563"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02253.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507063330105"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(98)90118-7"},{"key":"e_1_2_8_32_1","unstructured":"Centers for Disease Control and Prevention.CDC \u2010 Scabies \u2010 Resources for Health Professionals \u2010 Medications.https:\/\/www.cdc.gov\/parasites\/scabies\/health_professionals\/meds.html.Published2016. Accessed February 18 2019."},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMct0910329"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(06)70654-5"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.42.367"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.84063"},{"issue":"3","key":"e_1_2_8_37_1","first-page":"Cd000320","article-title":"Interventions for treating scabies","author":"Strong M","year":"2007","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.13077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tid.13077","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T10:18:58Z","timestamp":1694341138000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.13077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,29]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1111\/tid.13077"],"URL":"https:\/\/doi.org\/10.1111\/tid.13077","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"type":"print","value":"1398-2273"},{"type":"electronic","value":"1399-3062"}],"subject":[],"published":{"date-parts":[[2019,3,29]]},"assertion":[{"value":"2019-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13077"}}