{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:40:13Z","timestamp":1761129613853,"version":"3.41.2"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Histoplasma capsulatum<\/jats:italic> is an endemic fungus that most oftenly causes a self\u2010limiting illness but can result in severe infections in immunocompromised patients including pulmonary or extra\u2010pulmonary disease. Rarely it can also cause a chronic progressive infection of the larynx. Herein, we report a case of laryngeal histoplasmosis in a kidney transplant patient who presented with progressive symptoms of several weeks of hoarseness, dysphagia and odynophagia. Laryngoscopic examination revealed thick plaques in the oropharynx with surrounding hyper\u2010erythema and histopathology showed numerous intracellular yeasts forms consistent with <jats:italic>H\u00a0capsulatum<\/jats:italic>. Patient was initiated on treatment with itraconazole. Infection of the larynx due to <jats:italic>H\u00a0capsulatum<\/jats:italic> is highly uncommon and therefore can result in an inappropriate or delayed diagnosis. A review of literature showed four previously reported cases of laryngeal histoplasmosis in patients with solid organ transplant. This is the first case series of laryngeal histoplasmosis in transplant recipients.<\/jats:p>","DOI":"10.1111\/tid.13102","type":"journal-article","created":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T22:48:18Z","timestamp":1557269298000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Laryngeal histoplasmosis in a kidney transplant recipient"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5960-7187","authenticated-orcid":false,"given":"Sarwat","family":"Khalil","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine Mayo Clinic College of Medicine and Science Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas W.","family":"Challener","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine Mayo Clinic College of Medicine and Science Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Abu\u2010Saleh","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine Mayo Clinic College of Medicine and Science Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Rizwan","family":"Sohail","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine Mayo Clinic College of Medicine and Science Rochester Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1906.62510440037003"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004732"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03493.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200010193431605"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/604712"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00658.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1983.00350040093012"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-8365.2005.00105.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit593"},{"key":"e_1_2_6_11_1","unstructured":"RobayoC.Laryngeal Histoplasmosis: report first case in Colombia. 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