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We report a case of TS 6\u00a0months after kidney transplantation in a 65\u00a0years\u2010old woman under immunosuppression therapy with prednisone, mycophenolate and tacrolimus. The patient developed follicular papules on the face with a thickening of the skin and alopecia of the eyebrows, leading to distortion of the face and a leonine appearance characteristic of the disease. The skin biopsy confirmed the clinical diagnosis and the presence of TSPyV DNA in the skin was detected. Staining for SV40 was positive. Immunosuppression was changed: mycophenolate was withdrawn, tacrolimus reduced and everolimus added. Intravenous cidofovir and later on leflunomide were added. Although the literature has reported clinical success with topical cidofovir, we were unable to use it because this drug is not available. There was an improvement of skin lesions and on cosmetic appearance. The patient had three rejections (one clinically diagnosed and two other biopsy proven), progressed with renal failure and graft loss. Retrospective analysis of stored urine and blood samples detected TSPyV DNA in some of those samples two months before the TS clinical development. This case highlights the TSPyV detection in blood and urine samples before the development of skin lesions.<\/jats:p>","DOI":"10.1111\/tid.13133","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T15:40:28Z","timestamp":1561477228000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Viremia and viruria of trichodysplasia spinulosa\u2010associated polyomavirus before the development of clinical disease in a kidney transplant recipient"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0216-3028","authenticated-orcid":false,"given":"Ligia Camera","family":"Pierrotti","sequence":"first","affiliation":[{"name":"Departamento de Doen\u00e7as Infecciosas e Parasit\u00e1rias, Faculdade de Medicina, Hospital das Cl\u00ednicas Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo 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