{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:35:29Z","timestamp":1753878929368,"version":"3.41.2"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T00:00:00Z","timestamp":1563753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Post\u2010transplant lymphoproliferative disorder (PTLD) is an uncommon, but well\u2010described complication after liver transplantation. Most recently, Hepatitis C virus (HCV) has been implicated in the development of PTLD. A HCV\u2010negative 62\u2010year\u2010old man with autoimmune hepatitis received a HCV nucleic acid amplification test\u2010positive liver graft from a 73\u2010year\u2010old brain\u2010dead donor (D+\/R\u2212). After his recovery from the operation, the patient was treated for HCV and achieved an undetectable viral load. He was readmitted 6\u00a0months after transplant with a spontaneous perisplenic hematoma, weight loss, failure to thrive, low\u2010grade fevers, and abnormal liver function tests. He had a rapid clinical deterioration and expired shortly after admission. His liver biopsy demonstrated EBV\u2010negative monomorphic B\u2010cell PTLD. Our case is the first to report an aggressive early\u2010onset EBV\u2010negative monomorphic B\u2010cell PTLD in a HCV D+\/R\u2212 liver transplant. This case illustrates the paucity of knowledge on HCV seroconversion and its involvement in EBV\u2010negative monomorphic B\u2010cell PTLD development.<\/jats:p>","DOI":"10.1111\/tid.13144","type":"journal-article","created":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T20:28:55Z","timestamp":1562790535000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Aggressive Epstein\u2010Barr virus\u2010negative B\u2010cell post\u2010transplant lymphoproliferative disorder in a hepatitis C\u2010negative liver transplant recipient who received a hepatitis C\u2010positive graft: Implications for D+\/R\u2212 hepatitis C virus seroconversion"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0106-9822","authenticated-orcid":false,"given":"Heather L.","family":"Kutzler","sequence":"first","affiliation":[{"name":"Hartford Hospital Transplant &amp; Comprehensive Liver Center Hartford 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