{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T15:25:58Z","timestamp":1773847558708,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T00:00:00Z","timestamp":1570060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Kidney transplantation is the gold\u2010standard therapy for select HIV\u2010positive patients with ESRD. Since the Italian Ministry of Health defined the guidelines for organ donation from HIV\u2010positive persons in 2018, we report the first case of renal transplantation from an HIV\u2010positive cadaveric donor in two HIV\u2010positive recipients in Italy. The donor was a 50\u2010year\u2010old male, deceased due to post\u2010anoxic encephalopathy, with a history of HIV infection in HAART, undetectable viral load, and HCV\u2010related chronic hepatitis that had been previously treated. The first recipient was a 59\u2010year\u2010old female with a prior history of drug addiction, and she suffered from ESRD secondary to HIV nephropathy. The patient followed preoperative HAART with a good viral response and undetectable HIV viral load. She also had a history of HCV\u2010related chronic hepatitis that had been successfully treated. The right kidney was uneventfully transplanted. The patient developed an asymptomatic reinfection of endogenous BK virus. The second recipient was a 41\u2010year\u2010old male with ESRD secondary to polycystic kidney disease. The patient was HIV\u2010positive in HAART, with a good viro\u2010immunologic response and an undetectable HIV viral load. He suffered from a severe form of hemophilia A and HCV\u2010related chronic hepatitis, which had been previously treated with undetectable HCV RNA. The left kidney was uneventfully transplanted. At the end of follow\u2010up, both patients had a healthy condition with stable renal function, a persistently good viral response and undetectable HIV and HCV viral loads. These encouraging preliminary results seem to confirm the safety and effectiveness of kidney transplantation from select HIV\u2010positive donors.<\/jats:p>","DOI":"10.1111\/tid.13183","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T22:57:31Z","timestamp":1569711451000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Kidney transplantation from an HIV\u2010positive cadaveric donor"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9966-9449","authenticated-orcid":false,"given":"Giovanni","family":"Varotti","sequence":"first","affiliation":[{"name":"Kidney Transplant Unit San Martino University Hospital Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"Dodi","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease San Martino University Hospital Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Boscaneanu","sequence":"additional","affiliation":[{"name":"Kidney Transplant Unit San Martino University Hospital Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Terulla","sequence":"additional","affiliation":[{"name":"Kidney Transplant Unit San Martino University Hospital Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Sambuceti","sequence":"additional","affiliation":[{"name":"Kidney Transplant Unit San Martino University Hospital Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Fontana","sequence":"additional","affiliation":[{"name":"Kidney Transplant Unit San Martino University Hospital Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu919"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1681\/ASN.V1071566","article-title":"Hepatitis C virus\u2013associated glomerular disease in patients with human immunodeficiency virus coinfection","volume":"10","author":"Cheng JT","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.10.1179"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000171410.76607.f8"},{"issue":"21","key":"e_1_2_6_6_1","first-page":"2070","article-title":"HIV\u2010positive\u2010to\u2010HIV\u2010positive kidney transplantation","volume":"372","author":"Muller E","year":"2015","journal-title":"N Engl J Med"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/2054358117695792"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfx109"},{"key":"e_1_2_6_9_1","unstructured":"[https:\/\/www.gazzettaufficiale.it\/eli\/id\/2018\/03\/08\/18A01639\/SG. 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