{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:48:06Z","timestamp":1780922886107,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T00:00:00Z","timestamp":1576195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intestinal and multivisceral transplantations are treatment options for patients with intestinal failure. Transplantation is often complicated by abdominal and\/or bloodstream infections in the post\u2010operative period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective chart review of all adults who underwent intestinal or multivisceral transplantation at our institution from 2003 to 2015 was performed. Data were collected for 2\u00a0years post transplant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 106 intestinal or multivisceral transplants were performed in 103 patients. The median age at the time of transplant was 44 (IQR: 34\u201052) with 55% (n\u00a0=\u00a058) male and 45% (n\u00a0=\u00a048) female. There were 46 (43%) intra\u2010abdominal infections post transplant among the 103 patients, and six transplant recipients (13%) developed concurrent bloodstream infections. The median time to first intra\u2010abdominal infection was 23\u00a0days (IQR: 10\u201048). For those with organisms isolated in culture, forty\u2010seven percent of the isolates were gram negative, 39% gram positive, 7% anaerobes, and 7% yeast. The most common isolates were enterococci at 28%, <jats:italic>E.\u00a0coli<\/jats:italic> at 14%, and <jats:italic>Klebsiella<\/jats:italic> spp at 13%. Sixty\u2010three percent of the enterococci were vancomycin\u2010resistant enterococci (VRE), and 22% of the gram\u2010negative isolates were extended spectrum beta\u2010lactamases (ESBLs). Patients with intra\u2010abdominal infections had longer hospital post\u2010transplant length of stays at a median of 35\u00a0days (IQR: 25\u201048) vs 23\u00a0days (IQR: 17\u201033) for those without infections,<jats:italic> P<\/jats:italic>\u00a0=\u00a0.0012. There was no difference in all\u2010cause mortality in patients with or without intra\u2010abdominal infections, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.654.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Intra\u2010abdominal infections are common in intestinal or multivisceral transplant recipients, but despite this complication, we found no increased risk of mortality. These transplant recipients are also at risk for infection with drug\u2010resistant organisms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13219","type":"journal-article","created":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T12:55:10Z","timestamp":1574945710000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Intra\u2010abdominal infections among adult intestinal and multivisceral transplant recipients in the 2\u2010year post\u2010operative period"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9011-8456","authenticated-orcid":false,"given":"Amanda Blair","family":"Spence","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases and Travel Medicine Department of Medicine Georgetown University Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhuri","family":"Natarajan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Travel Medicine Department of Medicine Georgetown University Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Fogleman","sequence":"additional","affiliation":[{"name":"School of Medicine Georgetown University Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshni","family":"Biswas","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Travel Medicine Department of Medicine Georgetown University Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Girlanda","sequence":"additional","affiliation":[{"name":"Medstar Georgetown Transplant Institute Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Timpone","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Travel Medicine Department of Medicine Georgetown University Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804605"},{"key":"e_1_2_7_3_1","unstructured":"UNOS.Data.https:\/\/unos.org\/data\/. Accessed April 30 2019."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-010-4324-y"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12812"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000185622.91708.57"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12979"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12107"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00683.x"},{"issue":"68","key":"e_1_2_7_10_1","first-page":"234","article-title":"Bacterial infections after intestine and multivisceral transplantation. The experience of the University of Miami (1994\u20132001)","volume":"53","author":"Loinaz C.","year":"2006","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14208"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12593"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)01189-1"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2003.12.004"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.06.061"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24486"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofx163.1904"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2016.1213472"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13219","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tid.13219","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T05:22:40Z","timestamp":1694064160000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.13219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,13]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/tid.13219"],"URL":"https:\/\/doi.org\/10.1111\/tid.13219","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,13]]},"assertion":[{"value":"2019-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13219"}}