{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T11:57:06Z","timestamp":1764331026381,"version":"3.41.2"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T00:00:00Z","timestamp":1582675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cerebral abscess due to pigmented molds is a rare but usually fatal infection occasionally seen in transplant recipients. A 67\u2010year\u2010old man of Iraqi origin underwent a deceased donation renal transplant for renal failure and 2\u00a0months later was diagnosed with an abscess in the left posterior frontal lobe of his brain. Subsequent biopsy proved this to be due to the mold <jats:italic>Rhinocladiella mackenziei.<\/jats:italic> Further interventions included two operations to aspirate the lesion, voriconazole, then liposomal amphotericin B, then a combination of posaconazole and flucytosine which he continued for over 4\u00a0years. He also suffered from right ankle pain and was diagnosed with septic arthritis; <jats:italic>R\u00a0mackenziei<\/jats:italic> was isolated from pus aspirated from the ankle joint. He responded well to the treatment and has had little loss of function, and on CT, the cerebral lesion has stabilized. Beta\u2010D\u2010glucan, initially at very high levels proved useful to monitor response over the 5\u00a0years and the latest sample was negative (38\u00a0pg\/mL). This case is notable for the first disseminated case of this infection, its favorable outcome on a novel antifungal combination and a new approach to monitoring the course of disease.<\/jats:p>","DOI":"10.1111\/tid.13264","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T16:19:47Z","timestamp":1581610787000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prolonged survival after disseminated <i>Rhinocladiella<\/i> infection treated with surgical excision and posaconazole"],"prefix":"10.1111","volume":"22","author":[{"given":"Nicola","family":"Hardman","sequence":"first","affiliation":[{"name":"Department of Microbiology Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Microbiology Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Hobson","sequence":"additional","affiliation":[{"name":"Department of Microbiology Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Sandoe","sequence":"additional","affiliation":[{"name":"Department of Microbiology Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Wellberry\u2010Smith","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Thomson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4811-2496","authenticated-orcid":false,"given":"Richard","family":"Barton","sequence":"additional","affiliation":[{"name":"Mycology Reference Centre Leeds Teaching Hospitals Trust Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70131-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12734"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01184-19"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0507.2003.00956.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/380635"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182a64db9"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.5.1216-1223.1997"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780400011104"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.5.1159-1162.2000"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693780903383914"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00009-09"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof5030060"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.13264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tid.13264","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T09:13:49Z","timestamp":1693818829000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.13264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,26]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1111\/tid.13264"],"URL":"https:\/\/doi.org\/10.1111\/tid.13264","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"type":"print","value":"1398-2273"},{"type":"electronic","value":"1399-3062"}],"subject":[],"published":{"date-parts":[[2020,2,26]]},"assertion":[{"value":"2019-10-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13264"}}