{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T21:54:30Z","timestamp":1783029270265,"version":"3.54.6"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T00:00:00Z","timestamp":1591574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Following a major seasonal outbreak of H1N1 influenza in 2018 September, prophylactic oseltamivir for six months was initiated in children undergoing haploidentical HCT with regular monitoring for influenza and other respiratory virus infections. Influenza was not detected in 22 children undergoing prophylaxis, compared to 8 H1N1 infections in 21 adults without prophylaxis (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.01). Four children on prophylaxis were detected to have other respiratory viruses, compared to 8 in those without prophylaxis. Invasive pulmonary aspergillosis (IPA) was observed only in association with H1N1 (4\/8 with H1N1 vs 0\/35 without H1N1, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001) and was thus lower in the prophylaxis group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.04). The overall incidence of episodes of respiratory illness and hospital stay were also lower in those on prophylaxis (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.001). There were no untoward side effects associated with prophylactic oseltamivir. Prophylactic oseltamivir was safe and effective in prevention of H1N1 infection and subsequent IPA in children at\u2010risk, early after haploidentical HCT.<\/jats:p>","DOI":"10.1111\/tid.13309","type":"journal-article","created":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T08:07:26Z","timestamp":1588925246000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prophylactic oseltamivir during major seasonal influenza H1N1 outbreak might reduce both H1N1 and associated pulmonary aspergillosis in children undergoing haploidentical transplantation"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9988-3514","authenticated-orcid":false,"given":"Sarita Rani","family":"Jaiswal","sequence":"first","affiliation":[{"name":"Cellular Therapy and Immunology Manashi Chakrabarti Foundation Kolkata India"},{"name":"Department of Blood and Marrow Transplantation &amp; Hematology Dharamshila Narayana Superspeciality Hospital and Research Centre New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gitali","family":"Bhagwati","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Dharamshila Narayana Super\u2010speciality Hospital New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayank","family":"Soni","sequence":"additional","affiliation":[{"name":"Department of Blood and Marrow Transplantation &amp; Hematology Dharamshila Narayana Superspeciality Hospital and Research Centre New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul","family":"Thatai","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics and R&amp;D Dr LalPathLabs Ltd New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemamalini","family":"Aiyer","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Dharamshila Narayana Super\u2010speciality Hospital New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suparno","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"Cellular Therapy and Immunology Manashi Chakrabarti Foundation Kolkata India"},{"name":"Department of Blood and Marrow Transplantation &amp; Hematology Dharamshila Narayana Superspeciality Hospital and Research Centre New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12116"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.041913"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2015.11.015"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12054"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2010.09.014"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy874"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02636-10"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002941"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP2192"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/518985"},{"issue":"2","key":"e_1_2_9_12_1","first-page":"103","article-title":"Oseltamivir prophylaxis during the influenza season in a paediatric cancer centre: prospective observational study","volume":"10","author":"Chik KW","year":"2004","journal-title":"Hong Kong Med J"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-500X.81901"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2011.09.002"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(18)30274-1"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00487"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000504"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftid.13309","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13309","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tid.13309","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T05:29:48Z","timestamp":1693805388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.13309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,8]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/tid.13309"],"URL":"https:\/\/doi.org\/10.1111\/tid.13309","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,8]]},"assertion":[{"value":"2020-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13309"}}