{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T18:51:56Z","timestamp":1773687116159,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The objective was to assess the oral shedding and viremia of human herpesviruses in renal transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a cohort study in which the participants were examined in three different periods: the first within 24\u00a0hours before renal transplantation and the second and third ones 15\u201020 and 45\u201060\u00a0days after the transplantation. Mouthwash and blood samples were collected in each period and then submitted to screening for the presence of eight types of human herpesviruses by using multiplex PCR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>HSV\u20101 and EBV were more frequent in the saliva after renal transplantation, 15\u2010 to 20\u2010day period after the transplant. EBV was found in the saliva of 26 (35.6%) patients before renal transplantation and in 56.2% and 46.6% of them, in the 15\u2010 to 20\u2010day and 45\u2010 to 60\u2010day periods after the transplant, respectively. High detection rates (75.3%\u201078.1%) were found for HHV\u20107 despite the lack of significant variations between the study periods. There was no concordance between herpesviruses oral shedding and viremia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We concluded that the pattern of excretion of HSV\u20101 and EBV in saliva is changed immediately after renal transplantation, increasing in the 15\u2010 to 20\u2010day period after the transplant surgery. No concordance between herpesviruses oral shedding and viremia was observed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13330","type":"journal-article","created":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T10:45:15Z","timestamp":1589712315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Herpesviruses oral shedding and viremia in renal transplant recipients: A longitudinal study"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7972-9141","authenticated-orcid":false,"given":"Dmitry Jos\u00e9 de Santana","family":"Sarmento","sequence":"first","affiliation":[{"name":"Department of Stomatology School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00e2nia Regina","family":"Tozetto\u2010Mendoza","sequence":"additional","affiliation":[{"name":"Laboratory of Virology School of Medicine 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