{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T20:52:49Z","timestamp":1780087969731,"version":"3.54.0"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T00:00:00Z","timestamp":1593129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Limited data are currently available regarding the course of COVID\u201019 in lung and solid organ transplant recipients. We hereby present four cases of SARS\u2010CoV\u20102 pneumonia in lung transplant recipients from our center, set in Milan, Italy. We reduced immunosuppressive regimen in all these patients, typically holding the antiproliferative agent and augmenting steroids; everybody received hydroxychloroquine, initial empiric antibiotic treatment with piperacillin\/tazobactam, and high\u2010dose low molecular weight heparin. Clinical course seemed favorable in three of our patients, but one of them deteriorated after 10\u00a0days of hospitalization, probably due to an acute form of graft dysfunction triggered both by COVID\u201019 and a nosocomial bacterial infection, and eventually died. Although short\u2010term prognosis could be considered benign in the majority of our patients, we should carefully monitor these individuals in order to detect early sign of clinical deterioration and graft dysfunction in the next few months.<\/jats:p>","DOI":"10.1111\/tid.13356","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T13:59:01Z","timestamp":1591624741000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["COVID\u201019 in lung transplant recipients: A case series from Milan, Italy"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4661-6471","authenticated-orcid":false,"given":"Letizia Corinna","family":"Morlacchi","sequence":"first","affiliation":[{"name":"Respiratory Unit and Adult Cystic Fibrosis Centre Internal Medicine Department Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Rossetti","sequence":"additional","affiliation":[{"name":"Respiratory Unit and Adult Cystic Fibrosis Centre Internal Medicine Department Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Gigli","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease Unit Internal Medicine Department Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Amati","sequence":"additional","affiliation":[{"name":"Respiratory Unit and Adult Cystic Fibrosis Centre Internal Medicine Department Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Rosso","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"},{"name":"Thoracic Surgery and Lung Transplant Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Aliberti","sequence":"additional","affiliation":[{"name":"Respiratory Unit and Adult Cystic Fibrosis Centre Internal Medicine Department Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Nosotti","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"},{"name":"Thoracic Surgery and Lung Transplant Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Blasi","sequence":"additional","affiliation":[{"name":"Respiratory Unit and Adult Cystic Fibrosis Centre Internal Medicine Department Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano Milano Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,26]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"SaimaA Danziger\u2010IzakovL LuongML 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