{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:50:38Z","timestamp":1773312638546,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T00:00:00Z","timestamp":1596499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The impact of coronavirus disease\u201019 (COVID\u201019) in liver recipients remains largely unknown. Most data derive from small retrospective series of patients transplanted years ago. We aimed to report a single\u2010center case series of five consecutive patients in the early postoperative period of deceased\u2010donor liver transplantation who developed nosocomial COVID\u201019. Two patients presented important respiratory discomfort and eventually died. One was 69\u00a0years old and had severe coronary disease. She rapidly worsened after COVID\u201019 diagnosis on 9th postoperative day. The other was 67\u00a0years old with non\u2010alcoholic steatohepatitis, who experienced prolonged postoperative course, complicated with cytomegalovirus infection and kidney failure. He was diagnosed on 36th postoperative day and remained on mechanical ventilation for 20\u00a0days, ultimately succumbing of secondary bacterial infection. The third, fourth, and fifth patients were diagnosed on 10th, 11th, and 18th postoperative day, respectively, and presented satisfactory clinical evolution. These last two patients were severely immunosuppressed, since one underwent steroid bolus for acute cellular rejection and another also used anti\u2010thymocyte globulin for treating steroid\u2010resistant rejection. Our novel experience highlights that COVID\u201019 may negatively impact the postoperative course, especially in elder and obese patients with comorbidities, and draws attention to COVID\u201019 nosocomial spread in the early postoperative period.<\/jats:p>","DOI":"10.1111\/tid.13418","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T15:08:58Z","timestamp":1594825738000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Liver transplant recipients infected with SARS\u2010CoV\u20102 in the early postoperative period: Lessons from a single center in the epicenter of the pandemic"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4284-0633","authenticated-orcid":false,"given":"Daniel Reis","family":"Waisberg","sequence":"first","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0765-6654","authenticated-orcid":false,"given":"Edson","family":"Abdala","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Department of Infectious and Parasitic diseases Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7059-3978","authenticated-orcid":false,"given":"Lucas Souto","family":"Nacif","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana Bertocco","family":"Haddad","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo 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Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa Nunes","family":"Gouveia","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Department of Infectious and Parasitic diseases Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina Santos","family":"Lazari","sequence":"additional","affiliation":[{"name":"Division of Central Laboratory Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Bronze","family":"Martino","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael Soares","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rubens Macedo","family":"Arantes","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory of Medical Investigation 37 (LIM\u201037) Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debora Raquel","family":"Terrabuio","sequence":"additional","affiliation":[{"name":"Liver and Abdominal Organs Transplantation Division Department of Gastroenterology Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HC\u2010FMUSP) S\u00e3o Paulo Brazil"},{"name":"Laboratory 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