{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:43:07Z","timestamp":1761129787093,"version":"3.41.2"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Talaromycosis is a fungal infection endemic in Southeast Asia. We report a case of a renal transplant recipient who developed infection after a trip to South China. She presented with constitutional symptoms and was found to have an FDG\u2010avid lung mass. Histopathology demonstrated small yeast cells and culture grew <jats:italic>Talaromyces marneffei<\/jats:italic>. The patient was treated with 2\u00a0weeks of liposomal amphotericin B followed by itraconazole. The dose of tacrolimus was significantly reduced because of the interaction with itraconazole. Mycophenolate mofetil was discontinued. After 12\u00a0months of treatment, the mass had completely resolved. Talaromycosis has mainly been reported in patients with AIDS and is uncommon among solid organ transplant recipients. The immune response against <jats:italic>T. marneffei<\/jats:italic> infection is mediated predominantly by T cells and macrophages. The diagnosis may not be suspected outside of endemic areas. We propose a therapeutic approach in transplant patients by extrapolating the evidence from the HIV literature and following practices applied to other endemic mycoses.<\/jats:p>","DOI":"10.1111\/tid.13447","type":"journal-article","created":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T15:48:26Z","timestamp":1597420106000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Talaromycosis in a renal transplant recipient returning from South China"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6581-3956","authenticated-orcid":false,"given":"Paschalis","family":"Vergidis","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Mayo Clinic Rochester MN USA"},{"name":"William J von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anirudh","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine and Transplant Nephrology Royal Liverpool and Broadgreen University Hospitals Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline B.","family":"Moore","sequence":"additional","affiliation":[{"name":"Mycology Reference Centre Manchester ECMM Excellence Centre Wythenshawe Hospital Manchester University NHS Foundation Trust Manchester UK"},{"name":"Division of Infection, Immunity and Respiratory Medicine School of Biological Sciences Faculty of Biology, Medicine and Health University of Manchester Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riina","family":"Rautemaa\u2010Richardson","sequence":"additional","affiliation":[{"name":"Mycology Reference Centre Manchester ECMM Excellence Centre Wythenshawe Hospital Manchester University NHS Foundation Trust Manchester UK"},{"name":"Division of Infection, Immunity and Respiratory Medicine School of Biological Sciences Faculty of Biology, Medicine and Health University of Manchester Manchester UK"},{"name":"Department of Infectious Diseases Wythenshawe Hospital Manchester University NHS Foundation Trust Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise C.","family":"Sweeney","sequence":"additional","affiliation":[{"name":"Department of Microbiology Manchester University NHS Foundation Trust Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muir","family":"Morton","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine and Transplant Nephrology Manchester University NHS Foundation Trust Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Public Health England UK National Mycology Reference Laboratory 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