{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:42:07Z","timestamp":1760647327683,"version":"3.41.2"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Kidney transplant recipients have been supposed vulnerable to severe Covid\u201019 infection, due to their comorbidities and immunosuppressive therapies. Mild\u2010term complications of Covid\u201019 are currently unknown, especially in this population. Herein, we report two cases of BKV replication after non\u2010severe SARS\u2010CoV\u20102 infection. The first case was a 59\u2010year\u2010old man, transplanted 3\u00a0months ago, with recent history of slight BKV viremia (3.3 log<jats:sub>10<\/jats:sub> DNA copies\/ml). Despite strong reduction of maintenance immunosuppression (interruption of mycophenolic acid and important decrease of calcineurin inhibitors), BKV replication largely increased after Covid\u201019 and viremia persisted at 4.5 log copy\/ml few months later. The second case was a 53\u2010year\u2010old woman, transplanted 15\u00a0years ago. She had a recent history of BKV cystitis, which resolved with a decrease of MPA dosage. Few weeks after SARS\u2010CoV\u20102 infection, she presented recurrence of lower urinary tract symptoms. Our reports highlight that SARS\u2010CoV\u20102 infection, even without severity, could disrupt immune system and particularly lymphocytes, thus leading to viral replication. Monitoring of viral replications after Covid\u201019 in kidney transplant recipients could permit to confirm these preliminary observations.<\/jats:p>","DOI":"10.1111\/tid.13465","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T03:19:19Z","timestamp":1600312759000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Resurgence of BK virus following Covid\u201019 in kidney transplant recipients"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7442-2164","authenticated-orcid":false,"given":"Christophe","family":"Masset","sequence":"first","affiliation":[{"name":"Nephrology and Transplantation Department Centre Hospitalier Universitaire Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Ville","sequence":"additional","affiliation":[{"name":"Nephrology and Transplantation Department Centre Hospitalier Universitaire Nantes France"},{"name":"Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM Universit\u00e9 de Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0336-9615","authenticated-orcid":false,"given":"Franck","family":"Halary","sequence":"additional","affiliation":[{"name":"Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM Universit\u00e9 de Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Gaborit","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department Centre Hospitalier Universitaire Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celine","family":"Bressolette\u2010Bodin","sequence":"additional","affiliation":[{"name":"Service de Virologie Centre Hospitalier Universitaire Nantes 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Recherche en Transplantation et Immunologie UMR 1064 INSERM Universit\u00e9 de Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Cantarovich","sequence":"additional","affiliation":[{"name":"Nephrology and Transplantation Department Centre Hospitalier Universitaire Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7641-1592","authenticated-orcid":false,"given":"Magali","family":"Giral","sequence":"additional","affiliation":[{"name":"Nephrology and Transplantation Department Centre Hospitalier Universitaire Nantes France"},{"name":"Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM Universit\u00e9 de Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryvonne","family":"Hourmant","sequence":"additional","affiliation":[{"name":"Nephrology and Transplantation Department Centre Hospitalier Universitaire Nantes 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