{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:55:44Z","timestamp":1792032944608,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T00:00:00Z","timestamp":1603324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Data on the risk factors and outcome of intra\u2010abdominal fungal infections (IAFI) following simultaneous pancreas\u2010kidney transplantation (PKT) are scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials\/methods<\/jats:title><jats:p>A retrospective monocentric study was conducted on all patients who underwent simultaneous PKT from January 2007 to December 2016. Deep sites positive cultures for fungi during the first post\u2010transplantation year were collected. Clinical, radiological, and microbiological data of proven and probable invasive fungal infections were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among sixteen PKT patients, 15 were included. Seven patients (47%) developed an invasive fungal infection, exclusively IAFI (six proven, one probable). The proven IAFI included four peritonitis, one pancreatic necrosis with infected hematoma, and one patient with positive preservation fluid only (PF).<jats:italic>Candida albicans<\/jats:italic>(n\u00a0=\u00a04) was the most prevalent species (associated with<jats:italic>Galactomyces candidus<\/jats:italic>in one case),<jats:italic>C glabrata<\/jats:italic>,<jats:italic>C dubliniensis,<\/jats:italic>and<jats:italic>C krusei<\/jats:italic>were found in one case each. Three patients had either a positive direct examination and\/or culture for renal or pancreatic PF and the culture of PF was positive for the same species that caused IAFI. IAFIs were significantly associated with pancreatic graft arterial thrombosis (5\/7 vs 0\/8,<jats:italic>P<\/jats:italic>\u00a0=\u00a0.007) and fungal contamination of PF (3\/7 vs 0\/8,<jats:italic>P<\/jats:italic>\u00a0=\u00a0.008). Among patients with IAFI, all required an early surgical revision post\u2010transplantation [1\u201018\u00a0days] and six had early or delayed pancreatic graft removal. One patient died in the first post\u2010transplant year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>IAFI is a common complication in PKT, associated with pancreatic graft thrombosis or fungal contamination of the graft PF, and can sometimes lead to pancreatic detransplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13486","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T02:16:00Z","timestamp":1602555360000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Risk factors for intra\u2010abdominal fungal infection after simultaneous pancreas\u2010kidney transplantation: A single\u2010center retrospective experience"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7840-2104","authenticated-orcid":false,"given":"Clara","family":"Flateau","sequence":"first","affiliation":[{"name":"Service de maladies infectieuses 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