{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T13:59:00Z","timestamp":1782482340418,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Disseminated nocardiosis is a rare but growing concern in immunocompromised patients. Typical localizations include the lung, brain and\/or soft tissues, but laboratory confirmation of nocardiosis usually requires sampling of infected organs by invasive procedures such as bronchoalveolar lavage or brain biopsy. We report a case of disseminated nocardiosis occurring in a hematopoietic stem\u2010cell transplant recipient, with clinical lung and brain localizations. Examination of the thyroid gland was suggestive of a unilateral abscess. A culture of thyroid pus sampled by fine\u2010needle aspiration was positive for <jats:italic>Nocardia farcinica<\/jats:italic> and therefore avoided a more invasive procedure. The patient recovered after a six\u2010month antibiotic therapy without thyroid surgery. We reviewed other ten cases of thyroid nocardiosis published in the medical literature. Among the ten cases of disseminated nocardiosis established during the patient's lifetime including ours, six (60%) were asymptomatic and seven (70%) were confirmed by culture of the aspiration of thyroid pus. When disseminated nocardiosis is suspected, systematic examination for a thyroid abscess may help establish a microbiological diagnosis and prevent further invasive procedures.<\/jats:p>","DOI":"10.1111\/tid.13594","type":"journal-article","created":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T04:21:07Z","timestamp":1614658867000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Thyroid nocardiosis: Case report and review of the literature"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6960-6700","authenticated-orcid":false,"given":"Violaine","family":"Esnault","sequence":"first","affiliation":[{"name":"AP\u2010HP Service de maladies infectieuses et tropicales CHU Bic\u00eatre Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Wittnebel","sequence":"additional","affiliation":[{"name":"D\u00e9partement d\u2019h\u00e9matologie Gustave Roussy Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Pouillon","sequence":"additional","affiliation":[{"name":"AP\u2010HP Service de maladies infectieuses et tropicales CHU Bic\u00eatre Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocco","family":"Collarino","sequence":"additional","affiliation":[{"name":"AP\u2010HP Service de maladies infectieuses et tropicales CHU Bic\u00eatre Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Jaur\u00e9guiberry","sequence":"additional","affiliation":[{"name":"AP\u2010HP Service de maladies infectieuses et tropicales CHU Bic\u00eatre Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Chachaty","sequence":"additional","affiliation":[{"name":"Gustave Roussy service de microbiologie Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Gachot","sequence":"additional","affiliation":[{"name":"D\u00e9partement de m\u00e9decine Gustave Roussy Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9779-9044","authenticated-orcid":false,"given":"Benjamin","family":"Wyplosz","sequence":"additional","affiliation":[{"name":"AP\u2010HP Service de maladies infectieuses et tropicales CHU Bic\u00eatre Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012436"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.2.259-282.2006"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.34781"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2011.01.021"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2019.1702181"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.06.013"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(93)95937-E"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000356852"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000404"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2011.11.016"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01531-13"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/126.3.569"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.7.2323-2325.1999"},{"issue":"5","key":"e_1_2_8_15_1","first-page":"1306","article-title":"Nocardiosis in patients with systemic lupus erythematosus. The Singapore lupus study group","volume":"27","author":"Leong KP","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652005000600009"},{"issue":"6","key":"e_1_2_8_17_1","first-page":"1055","article-title":"Nocardiosis revealed by thyroid abscess and pneumonia in a liver transplant recipient","volume":"46","author":"Reechaipichitkul W","year":"2015","journal-title":"Southeast Asian J Trop Med Public Health"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13594","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tid.13594","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.13594","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T11:20:58Z","timestamp":1693221658000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.13594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,11]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/tid.13594"],"URL":"https:\/\/doi.org\/10.1111\/tid.13594","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,11]]},"assertion":[{"value":"2020-09-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13594"}}