{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:08:49Z","timestamp":1782817729667,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T00:00:00Z","timestamp":1617148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Systematic screening for, and treatment of, latent tuberculosis (TB) infection is recommended prior to kidney transplant. However, little is known about patient compliance with, or the safety profile of, preventive therapies used in clinical practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective observational study of patients who were eligible for kidney transplant and were evaluated for TB infection between January 2013 and June 2019 at the TB clinic of a tertiary care teaching hospital. All patient data were registered prospectively as part of our nurse\u2010led program before kidney transplant. We assessed completion rates, tolerance with therapy, development of TB, and associated workload.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1568 patients were referred to our TB clinic for evaluation. Preventive therapy was given to 385 patients and completed by 340 (88.3%). Of these, 89 (23.1%) experienced some intolerance, with 27 requiring full discontinuation. After a median follow\u2010up of 45\u00a0months (1426 patient\u2010years), 206 (53.5%) of the treated patients received a kidney transplant; only one patient, who failed to complete treatment, developed post\u2010transplant TB (7.01 cases per 10\u00a0000 patient\u2010years; 95% confidence interval, 0.35\u201034.59). Extra nurse or medical visits were required by 268 (69.6%) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the complexity and workload generated by patients with ESRD awaiting kidney transplant, preventive therapy for TB is effective in most cases. Our experience provides important evidence on the feasibility of preventive therapy for TB before kidney transplant when delivered as part of a comprehensive nurse\u2010led program.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13603","type":"journal-article","created":{"date-parts":[[2021,3,21]],"date-time":"2021-03-21T01:38:30Z","timestamp":1616290710000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Tuberculosis prevention in patients undergoing kidney transplantation: A nurse\u2010led program for screening and treatment"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7729-6864","authenticated-orcid":false,"given":"Maria D.","family":"Grijota\u2010Camino","sequence":"first","affiliation":[{"name":"Tuberculosis Unit Service of Infectious Diseases Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00faria","family":"Montero","sequence":"additional","affiliation":[{"name":"Service of Nephrology Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"},{"name":"Department of Clinical Sciences University of Barcelona L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Luque","sequence":"additional","affiliation":[{"name":"Tuberculosis Unit Service of Infectious Diseases Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"D\u00edaz\u2010Jurado","sequence":"additional","affiliation":[{"name":"Service of Nephrology Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00faria","family":"Sab\u00e9","sequence":"additional","affiliation":[{"name":"Tuberculosis Unit Service of Infectious Diseases Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"},{"name":"Department of Clinical Sciences University of Barcelona L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"P\u00e9rez\u2010Recio","sequence":"additional","affiliation":[{"name":"Tuberculosis Unit Service of Infectious Diseases Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Couceiro","sequence":"additional","affiliation":[{"name":"Service of Nephrology Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"},{"name":"Department of Clinical Sciences University of Barcelona L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences University of Barcelona L\u2019Hospitalet de Llobregat Spain"},{"name":"Service of Internal Medicine Parc Sanitari Sant Joan de D\u00e9u Sant Boi de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M.","family":"Cruzado","sequence":"additional","affiliation":[{"name":"Service of Nephrology Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"},{"name":"Department of Clinical Sciences University of Barcelona L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Santin","sequence":"additional","affiliation":[{"name":"Tuberculosis Unit Service of Infectious Diseases Bellvitge University Hospital\u2010Bellvitge Institute of Biomedical Research (IDIBELL) L\u2019Hospitalet de Llobregat Spain"},{"name":"Department of Clinical Sciences University of Barcelona L\u2019Hospitalet de Llobregat Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/347103"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2019.01.049"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001224"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00000712"},{"key":"e_1_2_7_6_1","unstructured":"Organizaci\u00f3n Mundial de la Salud. 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