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We report a rare case of cytomegalovirus (CMV)\u2010associated PMC in a 52\u2010year\u2010old female patient who had undergone kidney transplantation more than 20 years ago and was on low dose prednisolone and ciclosporin. She presented with an acute history of fever, lethargy, vomiting and diarrhoea on admission. Computed tomography of the abdomen showed extensive colitis, and colonoscopy revealed extensive pseudomembrane formation. Multiple tests for <jats:italic>Clostridium difficile<\/jats:italic> and other common microbiological causes of colitis were negative. CMV DNAemia and colonic biopsies confirmed the diagnosis of CMV colitis. The patient responded to prompt CMV treatment, as demonstrated by clinical, endoscopic, and histological response. While CMV is a common pathogen in the solid organ transplant population that is familiar to most transplant physicians, it may present atypically as PMC. Here, we review the literature on CMV\u2010associated PMC and its relevance to solid organ transplant recipients. To our knowledge, this is the first reported case of CMV\u2010associated PMC in a kidney transplant recipient.<\/jats:p>","DOI":"10.1111\/tid.13694","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T15:06:36Z","timestamp":1626707196000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cytomegalovirus\u2010associated pseudomembranous colitis in a kidney transplant recipient"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6166-1919","authenticated-orcid":false,"given":"Yi Yi","family":"Chua","sequence":"first","affiliation":[{"name":"Department of Renal Medicine Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0884-7076","authenticated-orcid":false,"given":"Quan Yao","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Singapore General Hospital  Singapore"},{"name":"SingHealth\u2010Duke NUS Transplant Centre SingHealth  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2419-0817","authenticated-orcid":false,"given":"Nye Thane","family":"Ngo","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5640-1079","authenticated-orcid":false,"given":"Thinesh Lee","family":"Krishnamoorthy","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Singapore General Hospital  Singapore"},{"name":"SingHealth\u2010Duke NUS Transplant Centre SingHealth  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0758-1560","authenticated-orcid":false,"given":"Sobhana","family":"Thangaraju","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Singapore General Hospital  Singapore"},{"name":"SingHealth\u2010Duke NUS Transplant Centre SingHealth  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5250-855X","authenticated-orcid":false,"given":"Terence","family":"Kee","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Singapore General Hospital  Singapore"},{"name":"SingHealth\u2010Duke NUS Transplant Centre SingHealth  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2456-0873","authenticated-orcid":false,"given":"Hei Man","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1007\/s10140-020-01750-z"},{"unstructured":"FilmArray gastrointestinal panel CE IVD reagent booklet \u2010 ITI0030.Biofire Diagnostics. 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