{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:42:49Z","timestamp":1793731369468,"version":"4.6.1"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T00:00:00Z","timestamp":1639180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>BK polyomavirus (BKV) is a common infection among kidney transplant recipients (KTR). Risk factors and outcomes based on donor characteristics remain largely unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, we aimed to analyze the impact of donor factors through a paired kidney analysis. We included 289 pairs of adult deceased donor transplants (578 KTRs total); each pair had received kidneys from the same donor. Recipient pairs were divided into three groups: \u201cno BK group\u201d if neither KTR developed BK viremia (<jats:italic>n<\/jats:italic>\u00a0=\u00a0336), \u201cdiscordant\u201d if the only one did (<jats:italic>n<\/jats:italic>\u00a0=\u00a0176), and \u201cconcordant\u201d if both did (<jats:italic>n<\/jats:italic>\u00a0=\u00a066). Acute rejection (AR), graft failure, and BK nephropathy (BKN) were outcomes of interest.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Donors in the concordant group were younger, had lower kidney donor profile index (KDPI), and were less likely to be donor after circulatory death (DCD). In multivariate analyses, KTRs who had a donor with a higher body mass index (BMI) (hazard ratio (HR): 0.97; 95% confidence interval (CI): 0.95\u20130.99; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.009) were less likely to develop BKV. Concordance was not associated with AR (HR: 0.83; 95% CI: 0.51\u20131.34; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.45), graft failure (HR: 1.77; 95% CI: 0.42\u20137.50; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.43), or BKN (HR: 1.02; 95% CI: 0.51\u20132.03; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.96).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our study suggests lower donor BMI is associated with BKV infection, and concordance or discordance between paired kidney recipients is not associated with poor outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13768","type":"journal-article","created":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T05:25:39Z","timestamp":1637904339000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Risk factors and outcomes of BK viremia among deceased donor kidney transplant recipients based on donor characteristics"],"prefix":"10.1111","volume":"24","author":[{"given":"Isabel","family":"Breyer","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ban","family":"Dodin","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7675-6128","authenticated-orcid":false,"given":"Arjang","family":"Djamali","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison Wisconsin 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