{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:02:44Z","timestamp":1778817764402,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The burden of sexually transmitted infections (STI) among solid\u2010organ transplant recipients is currently unknown. We studied the risk of STIs among kidney transplant recipients compared with the general population in a nationwide cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2002 and 2019, all microbiological findings of <jats:italic>Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum<\/jats:italic> (syphilis), and human immunodeficiency virus among kidney transplant recipients &lt;65 years and transplanted between 1995 and 2017 in our country were captured from statutory national registries. Data from the general population of Finland, population 5.5 million, were used for comparisons. Incidence of STIs and age and sex\u2010adjusted standardized incidence ratios (SIR) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Altogether 3612 transplantations, with a total follow\u2010up of 27\u00a0069 person\u2010years were included. A total of 30 STIs microbiological findings of STI were confirmed in 25 patients: <jats:italic>C. trachomatis<\/jats:italic> (<jats:italic>N<\/jats:italic> = 27)<jats:italic>, N. gonorrhoeae<\/jats:italic> (<jats:italic>N<\/jats:italic> = 2), and syphilis (<jats:italic>N<\/jats:italic> = 1). No hospitalizations associated with STIs were detected. The risk of STI after kidney transplantation was significantly lower compared to the general population (SIR, 0.57, 95% CI 0.39\u20130.80). The lower risk of STIs was more pronounced in female patients (SIR 0.40, 95% CI 0.20\u20130.74), whereas in male patients the difference was statistically not significant (SIR 0.69, 95% CI 0.44\u20131.04). Of the confirmed STI cases, 30% were detected in patients who received their transplants during adolescence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the Finnish kidney transplant population, the age and sex\u2010adjusted incidence of sexually transmitted infections is not higher compared to the general population. Highest frequency of infections was seen among patients transplanted during adolescence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13814","type":"journal-article","created":{"date-parts":[[2022,2,19]],"date-time":"2022-02-19T13:43:13Z","timestamp":1645278193000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Incidence of sexually transmitted infections is lower among kidney transplant recipients compared to the general population\u2014A nationwide cohort study"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2954-2538","authenticated-orcid":false,"given":"Ilkka","family":"Helanter\u00e4","sequence":"first","affiliation":[{"name":"Department of Transplantation and Liver Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8254-7525","authenticated-orcid":false,"given":"Mika","family":"Gissler","sequence":"additional","affiliation":[{"name":"Information Services Department Finnish Institute for Health and Welfare  Helsinki Finland"},{"name":"Department of Molecular Medicine and Surgery Karolinska Institute  Stockholm Sweden"},{"name":"Academic Primary Health Care Centre Region Stockholm  Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1993-2532","authenticated-orcid":false,"given":"Mari","family":"Kanerva","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruska","family":"Rimhanen\u2010Finne","sequence":"additional","affiliation":[{"name":"Information Services Department Finnish Institute for Health and Welfare  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-0064","authenticated-orcid":false,"given":"Marko","family":"Lempinen","sequence":"additional","affiliation":[{"name":"Department of Transplantation and Liver Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3742-1576","authenticated-orcid":false,"given":"Patrik","family":"Finne","sequence":"additional","affiliation":[{"name":"Department of Nephrology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16421"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16383"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12388"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15725"},{"key":"e_1_2_9_6_1","article-title":"Prevalence of sexually transmitted diseases in asymptomatic renal transplant recipients","author":"Sarier M","year":"2018","journal-title":"Exp Clin Transplant"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12554"},{"key":"e_1_2_9_8_1","first-page":"56","volume-title":"Cancer Epidemiology: Principles and Methods","author":"dos Santos Silva I","year":"1999"},{"key":"e_1_2_9_9_1","unstructured":"Statistics Finland;2020 https:\/\/www.stat.fi\/index_en.html accessed May 29th 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