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Understanding the spectrum of antifungal agents, their efficacy and safety profiles, and pharmacokinetics, as well as duration of therapy is hereby essential.<\/jats:p><jats:p>The most frequent IFIs in SOT recipients are caused by <jats:italic>Candida<\/jats:italic> species, followed by <jats:italic>Aspergillus<\/jats:italic> species, both with increasing resistance rates. Diagnosis of IFI can be challenging due to unspecific clinical presentation and difficult interpretation of microbiological findings and biomarkers. Prophylactic strategies, such as those for invasive aspergillosis in lung transplantation or invasive candidiasis (IC) in certain liver transplant settings, as well as the selection of the appropriate therapeutic agents require detailed knowledge on the pharmacokinetics and drug\u2013drug interactions of antifungals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Here in this review, we address what constitutes good AFS in this heterogeneous field of solid organ transplant recipients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13855","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T11:00:03Z","timestamp":1653044403000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Antifungal stewardship in solid organ transplantation"],"prefix":"10.1111","volume":"24","author":[{"given":"Lisa","family":"Kriegl","sequence":"first","affiliation":[{"name":"Division 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