{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:37:11Z","timestamp":1759412231459,"version":"3.41.2"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Assessing vaccine serologic status presents opportunities to provide live vaccinations to kidney transplant candidates (KTC). This is especially important given the increased risk of infection while taking lifelong immunosuppression following transplant and the inability to routinely provide live vaccines to patients on immunosuppressive medications. In March 2019, the American Society of Transplantation Infectious Disease Community of Practice (AST\u2010IDCOP) released updated guidelines for vaccination of KTC, which emphasize pretransplant viral serology screening and live vaccine administration prior to transplant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Primary Endpoint<\/jats:title><jats:p>The primary endpoint of this study was to determine adherence to AST\u2010IDCOP guidelines for live measles, mumps, and rubella (MMR) and VZV vaccination prior to transplant in KTC non\u2010immune by serology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective, descriptive study examined serologic status and rates of live vaccination in 672 patients listed for kidney transplant at our center between July 2014 and July 2019. Secondary endpoints included subgroup analysis of adherence to full AST\u2010IDCOP vaccination recommendations and validation of CDC presumed immunity definitions for measles and VZV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventeen patients (2.7%) were nonimmune by serology for VZV, while 182 (27.1%) were nonimmune by serology to MMR. In a subgroup analysis of the seronegative KTC, none received VZV vaccination, and 6% received MMR vaccination prior to transplant or last follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Overall, a large portion of KTC had immunity gaps that were not resolved before transplantation. These findings are limited due to the retrospective, single\u2010center nature of this study and should be confirmed with larger, prospective assessments of serologic status and vaccine administration.<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid13973-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13973","type":"journal-article","created":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T06:55:55Z","timestamp":1666248955000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Serologic evaluation of vaccine preventable infections and vaccination rates in kidney transplant candidates"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5521-2623","authenticated-orcid":false,"given":"Sabrina","family":"Schneider","sequence":"first","affiliation":[{"name":"Department of Pharmacy Services University of Utah Health Salt Lake City Utah USA"},{"name":"Department of Pharmacy Services University of Kansas Health Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3765-5882","authenticated-orcid":false,"given":"Adrian","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services University of Utah Health Salt Lake City Utah USA"},{"name":"Department of Pharmacy Services Medical University of South Carolina Lancaster Division South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9584-0584","authenticated-orcid":false,"given":"Bhanupriya","family":"Sirandas","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services University of Utah Health Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8447-6203","authenticated-orcid":false,"given":"Breanna","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services University of Utah Health Salt Lake City Utah USA"},{"name":"Department of Pharmacy Services Saint Luke's Hospital of Kansas City Kansas City Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2392-6036","authenticated-orcid":false,"given":"Crystal","family":"Truax","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services University of Utah Health Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.5500\/wjt.v9.i1.1"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13563"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2018.04.014"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra064928"},{"key":"e_1_2_11_6_1","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13529","article-title":"Establishing best practices in measles, mumps, and rubella serologic screening for kidney transplant candidates","volume":"23","author":"Ramakrishna JM","year":"2020","journal-title":"Transpl Infect Dis"},{"issue":"1","key":"e_1_2_11_7_1","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13202","article-title":"Serologic screening and infectious disease consultation (IDC): Indicated in heart, lung, liver (HLL) solid organ transplants (SOT) for measles, mumps, rubella, and varicella","volume":"22","author":"Seckin ZI","year":"2019","journal-title":"Transpl Infect Dis"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.1.35"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12534"},{"key":"e_1_2_11_10_1","unstructured":"KrogerA BahtaL HunterP et\u00a0al.General best practice guidelines for immunization: best practices guidance of the advisory committee on immunization practices (ACIP).2020. 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