{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:47:52Z","timestamp":1792165672443,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T00:00:00Z","timestamp":1670976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) pandemic has been raging since the end of 2019 and has shown worse outcomes in solid organ transplant (SOT) recipients. The clinical differences as well as outcomes between respiratory viruses have not been well defined in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective cohort study of adult SOT recipients with nasopharyngeal swab or bronchoalveolar lavage PCR positive for either SARS\u2010CoV\u20102, seasonal coronavirus, respiratory syncytial virus (RSV) or influenza virus from January 2017 to October 2020. The follow up period was 3 months. Clinical characteristics and outcomes were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 377 recipients including 157 SARS\u2010CoV\u20102, 70 seasonal coronavirus, 50 RSV and 100 influenza infections were identified. The most common transplanted organ was kidney 224\/377 (59.4%). Lower respiratory tract infection (LRTI) was found in 210\/377 (55.7%) and the risk factors identified with multivariable analysis were SARS\u2010CoV\u20102 infection, steroid use, and older age. Co\u2010 and secondary infections were seen in 77\/377 (20.4%) recipients with bacterial pathogens as dominant. Hospital admission was seen in 266\/377 (67.7%) recipients without significant statistical difference among viruses, however, ICU admission, mechanical ventilation and mortality were higher with SARS\u2010CoV\u20102 infection. In the multivariable model, the risk factors for mortality were SARS\u2010CoV\u20102 infection and older age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found higher incidence of ICU admission, mechanical ventilation, and mortality among SARS\u2010CoV\u20102 infected recipients. Older age was found to be the risk factor for lower respiratory tract infection and mortality for SARS\u2010CoV\u20102, coronaviruses, RSV and influenza virus groups.\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid13998-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.13998","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T19:23:04Z","timestamp":1670440984000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Difference between SARS\u2010CoV\u20102, seasonal coronavirus, influenza, and respiratory syncytial virus infection in solid organ transplant recipients"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3822-0669","authenticated-orcid":false,"given":"Maria A.","family":"Mendoza","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Infectious Disease University of Miami Miller School of Medicine Miami  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Motoa","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Disease University of Miami Miller School of Medicine Miami  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4324-5748","authenticated-orcid":false,"given":"Mohammed A.","family":"Raja","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Disease University of Miami Miller School of Medicine Miami  Miami Florida 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Jackson Health System  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve C.","family":"Courel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Disease University of Miami Miller School of Medicine Miami  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akina","family":"Natori","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Medical Oncology University of Miami Miller School of Medicine  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristopher B.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Miami Transplant Institute Jackson Health System  Miami Florida USA"},{"name":"Department of Medicine, Division of Hepatology University of Miami Miller School of Medicine  Miami Florida 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